多巴胺D3受体拮抗剂萘法朵特和PNU 99194A在动物模型中的抗焦虑样作用。
Anxiolytic-like effect of nafadotride and PNU 99194A, dopamine D3 receptor antagonists in animal models.
作者信息
Rogóz Z, Kłodzińska A, Maj J
机构信息
Department of Pharmacology, Polish Academy of Sciences, Kraków.
出版信息
Pol J Pharmacol. 2000 Nov-Dec;52(6):459-62.
PMID:11334239
Abstract
The obtained results indicate that dopamine D3 receptor antagonists, nafadotride and PNU 99194A, produced anxiolytic-like effect in animal models, which suggests a putative role of these drugs in the therapy of anxiety.
摘要
所获结果表明，多巴胺D3受体拮抗剂萘法朵屈和PNU 99194A在动物模型中产生了抗焦虑样效应，这表明这些药物在焦虑症治疗中可能具有一定作用。
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