McCutcheon I E, Kitagawa R H, Sherman S I, Bruner J M
Department of Neurosurgery, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
Neurosurgery. 2001 May;48(5):1161-5; discussion 1165-6. doi: 10.1097/00006123-200105000-00044.
A case of metastasis to the pituitary gland from a ductal adenocarcinoma of the salivary gland is presented. Metastasis to this site is rare, and a salivary gland source has never previously been described.
This patient presented with hypopituitarism, including diabetes insipidus.
A craniotomy was performed to alleviate visual loss. The histological features of the sellar tumor were identical to those of a tumor removed from the parotid gland 18 months earlier.
Although intrasellar tumors originating from embryonic rests of salivary gland tissue have been reported, metastasis from a malignant neoplasm arising within a true salivary gland is also possible and should not be excluded from consideration for patients in whom a salivary gland-like tumor is discovered in the sella turcica.
本文报告一例唾液腺导管腺癌转移至垂体的病例。转移至该部位较为罕见,此前从未有过唾液腺来源的相关描述。
该患者出现垂体功能减退,包括尿崩症。
进行了开颅手术以缓解视力丧失。蝶鞍区肿瘤的组织学特征与18个月前从腮腺切除的肿瘤相同。
尽管已有报告称蝶鞍内肿瘤起源于唾液腺组织的胚胎残余,但真正唾液腺内发生的恶性肿瘤转移也是可能的,对于在蝶鞍内发现类似唾液腺肿瘤的患者,不应排除这种可能性。