Liu He, Yamaki Toshiaki, Oka Shin-ichi, Koyanagi Izumi, Houkin Kiyohiro
Department of Neurosurgery, Sapporo Medical University School of Medicine, Japan.
Neurol Med Chir (Tokyo). 2005 Aug;45(8):418-22. doi: 10.2176/nmc.45.418.
A 54-year-old man, with a past history of renal cell carcinoma, presented with bitemporal visual field defect, hyponatremia, and diabetes insipidus. Endocrinological examination revealed panhypopituitarism. Computed tomography and magnetic resonance imaging showed an intrasellar mass with suprasellar extension. The initial radiological impression was pituitary adenoma. The tumor was decompressed via the transsphenoidal route. Histological examination revealed metastatic renal cell carcinoma. The clinical characteristics of metastatic pituitary carcinoma appear to be panhypopituitarism, and neuroimaging findings of strong enhancement of the tumor and bony destruction without marked sellar enlargement.
一名54岁男性,有肾细胞癌病史,出现双颞侧视野缺损、低钠血症和尿崩症。内分泌检查显示全垂体功能减退。计算机断层扫描和磁共振成像显示鞍内肿块并向鞍上延伸。最初的影像学印象是垂体腺瘤。通过经蝶窦途径对肿瘤进行减压。组织学检查显示为转移性肾细胞癌。转移性垂体癌的临床特征似乎是全垂体功能减退,以及肿瘤强化明显和骨质破坏而蝶鞍无明显增大的神经影像学表现。