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锥体束切断术对操作性条件反射大鼠的时间依赖性影响。

Time-dependent effects of pyramidotomy in the operantly conditioned rats.

作者信息

Fanardjian V V, Gevorkyan O V, Mallina R K, Melik-Moussian A B, Meliksetyan I B

机构信息

L.A. Orbeli Institute of Physiology, National Academy of Sciences of Armenia, 22 Orbeli Bros. Str., 375028, Yerevan, Armenia.

出版信息

Behav Brain Res. 2001 Aug 1;122(2):139-43. doi: 10.1016/s0166-4328(01)00159-0.

DOI:10.1016/s0166-4328(01)00159-0
PMID:11334644
Abstract

The effect of unilateral transection of bulbar pyramid on operantly conditioning in rats, have been shown to be in direct relationship with the time of its execution. Stable instrumental reflexes reappeared on average 3.9 days after the transection of the bulbar pyramid. However, preliminary transection of the pyramid led to the prolongation of stabilization of operant conditioning after an average of 16.5 days. These findings are considered to be in view of the mechanisms of switching of descending influences of corticospinal and cortico--rubrospinal systems.

摘要

延髓锥体单侧横断对大鼠操作性条件反射的影响,已被证明与其执行时间直接相关。延髓锥体横断后,稳定的工具性反射平均在3.9天后重新出现。然而,锥体的预先横断导致操作性条件反射稳定的平均时间延长至16.5天。这些发现是从皮质脊髓和皮质红核脊髓系统下行影响的转换机制方面来考虑的。

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