Finsterer J, Fuglsang-Frederiksen A
Ludwig Boltzmann Institute for Research in Epilepsy and Neuromuscular Disorders, Vienna, Austria.
Clin Neurophysiol. 2001 May;112(5):853-60. doi: 10.1016/s1388-2457(01)00499-0.
Little is known about the relation and sensitivity of macro-EMG (MA-EMG) compared with concentric-needle EMG (CN-EMG) in the detection of neuromuscular disorders.
CN-EMGs and MA-EMGs were recorded from the right brachial biceps muscle of 40 healthy subjects, aged 17-83 years, 20 patients with neurogenic disorders, aged 25-75 years, and 20 patients with myopathy, aged 18-76 years. Motor unit action potentials (MUAPs) were examined.
In patients with neurogenic disorders CN-MUAP duration, CN-MUAP amplitude, percent polyphasia, MA-MUAP amplitude, MA-MUAP area and fibre density were significantly increased. In patients with myopathy, only fibre density was significantly increased. In patients with neurogenic disorders, the sensitivity of CN-EMG was 80%, and that of MA-EMG 85%. In myopathies, the sensitivity was 50% for each technique. Pooling the results of both EMG techniques, the sensitivity increased to 90% in patients with neurogenic disorders, and to 65% in myogenic disease.
MA-EMG has a similar sensitivity in the detection of neuromuscular disorders as CN-EMG. Particularly when myopathy is suspected, both techniques should be applied if one is unrevealing.
与同心针电极肌电图（CN-EMG）相比，关于宏肌电图（MA-EMG）在检测神经肌肉疾病中的关系和敏感性知之甚少。
对40名年龄在17 - 83岁的健康受试者、20名年龄在25 - 75岁的神经源性疾病患者以及20名年龄在18 - 76岁的肌病患者的右侧肱二头肌进行CN-EMG和MA-EMG记录。检查运动单位动作电位（MUAPs）。
在神经源性疾病患者中，CN-MUAP持续时间、CN-MUAP波幅、多相波百分比、MA-MUAP波幅、MA-MUAP面积和纤维密度显著增加。在肌病患者中，仅纤维密度显著增加。在神经源性疾病患者中，CN-EMG的敏感性为80%，MA-EMG为85%。在肌病中，每种技术的敏感性均为50%。综合两种肌电图技术的结果，神经源性疾病患者的敏感性提高到90%，肌源性疾病患者提高到65%。
MA-EMG在检测神经肌肉疾病方面与CN-EMG具有相似的敏感性。特别是当怀疑有肌病时，如果一种技术无异常发现，两种技术都应应用。
