Gan R, Jabre J F
Department of Neurology, Boston University School of Medicine, Boston VA Outpatient Clinic, Massachusetts.
Muscle Nerve. 1992 Oct;15(10):1085-8. doi: 10.1002/mus.880151005.
In the second part of this study we investigate the correlations between the concentric and conmac action potentials in motor units of individuals with diseases of muscle and nerve. We studied 86 myopathic and 86 neurogenic motor units and compared their concentric and conmac action potentials. In the patients with myopathy, we found that the concentric motor unit action potential's (MUAP) area correlates strongly with the conmac potential, even better than in normals, while its amplitude correlates less. In the neurogenic group, we found that both the concentric MUAP's area and amplitude correlated very well with their conmac counterpart, more so than in normals. Thus, in pathology, as in normals, measuring the concentric MUAP's area in addition to its amplitude adds to the diagnostic sensitivity of motor unit potential measurements. These findings are discussed in light of the known dynamic and architectural motor unit changes which take place in the myopathic and neurogenic motor unit.
在本研究的第二部分，我们调查了患有肌肉和神经疾病个体的运动单位中同心针电极和同轴单极针电极动作电位之间的相关性。我们研究了86个肌病性运动单位和86个神经源性运动单位，并比较了它们的同心针电极和同轴单极针电极动作电位。在肌病患者中，我们发现同心针电极运动单位动作电位（MUAP）的面积与同轴单极针电极电位密切相关，甚至比正常人更好，而其波幅相关性较差。在神经源性组中，我们发现同心针电极MUAP的面积和波幅与其同轴单极针电极对应值相关性都很好，比正常人更显著。因此，在病理状态下，与正常情况一样，除了测量同心针电极MUAP的波幅外，测量其面积可提高运动单位电位测量的诊断敏感性。根据已知的在肌病性和神经源性运动单位中发生的动态和结构运动单位变化对这些发现进行了讨论。
