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[基于世界卫生组织建议的儿童结核病化疗经验]

[Experience in chemotherapy of tuberculosis in children based on WHO recommendations].

作者信息

Iukhimenko N V, Mitinskaia L A, Elufimova V F

出版信息

Probl Tuberk. 2001(1):24-8.

PMID:11337775
Abstract

WHO recommends that patients with primary intrathoracic tuberculosis fall into 4 categories by clinical symptoms, severity and spread of the process. They are to receive 2 staged treatment. The duration of each chemotherapy phase depends on the time of reverse development of the specific process regarding abacillarity of the primary tuberculosis by clinicoroentgenological dynamics. Therapy in children is completed after a full resolution of the pathological changes or upon stabilization of the process at the stage of residual changes when clinical laboratory evidence indicates absence of latent activity of the process. According to these WHO criteria 255 children aged 3 to 12 years were treated in the Central Research Institute of Tuberculosis for the last 10 years.

摘要

世界卫生组织建议,原发性胸内结核病患者根据临床症状、病情严重程度及病变扩散情况分为4类。他们需接受两阶段治疗。每个化疗阶段的时长取决于根据临床X线动态观察,原发性结核杆菌转阴的具体病程所需时间。儿童患者在病理变化完全消退后,或在病程稳定于残留变化阶段且临床实验室证据表明无潜在活动时,治疗结束。根据世界卫生组织的这些标准,在过去10年里,结核病中央研究院对255名3至12岁的儿童进行了治疗。

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