Szigeti N, Fábián G, Gömöri E, Czirják L
Pécsi Tudományegyetem, Altalános Orvostudományi Kar, II. Belgyógyászati Klinika.
Orv Hetil. 2001 Apr 1;142(13):671-4.
Systemic sclerosis is a generalized systemic autoimmune disorder frequently involving the oesophagus causing reflux oesophagitis in the majority of patients. Barrett's oesophagus is one of the most serious complication of the reflux oesophagitis, in which the normal oesophageal squamous epithelium is partially replaced by metaplastic columnar epithelium. The clinical significance of Barrett's oesophagus is the significantly increased risk of developing the adenocarcinoma. In our paper, the authors present 5 cases with Barrett's oesophagus among their 52 examined patients with scleroderma.
系统性硬化症是一种全身性自身免疫性疾病，常累及食管，导致大多数患者出现反流性食管炎。巴雷特食管是反流性食管炎最严重的并发症之一，其中正常食管鳞状上皮被化生的柱状上皮部分取代。巴雷特食管的临床意义在于发生腺癌的风险显著增加。在我们的论文中，作者在其检查的52例硬皮病患者中报告了5例巴雷特食管病例。
