Plotkin S A
University of Pennsylvania Wistar Institute, Doylestown, USA.
Arch Virol Suppl. 2001(17):121-34. doi: 10.1007/978-3-7091-6259-0_13.
Like varicella zoster virus (VZV), human cytomegalovirus (HCMV) causes disease after both primary and recurrent infections. The former is more serious, particularly in pregnant women, who may transmit the virus to their offspring, with a high risk of mental retardation and deafness. Various experimental vaccines are in development, ranging from live, attenuated HCMV, subunit envelope glycoprotein, poxvirus vectors with CMV genes inserted, and plasmid DANN.
与水痘带状疱疹病毒（VZV）一样，人巨细胞病毒（HCMV）在原发性感染和复发性感染后都会引发疾病。前者更为严重，尤其是在孕妇中，她们可能会将病毒传播给后代，导致后代有很高的智力迟钝和耳聋风险。目前正在研发各种实验性疫苗，包括减毒活HCMV疫苗、亚单位包膜糖蛋白疫苗、插入CMV基因的痘病毒载体疫苗以及质粒DNA疫苗。
