Motomura N, Takamoto S
Department of Cardiothoracic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
Nihon Geka Gakkai Zasshi. 2001 Apr;102(4):325-9.
The cryopreserved aortic homograft valve is one of the most reliable of the stentless biological prosthesis if implanted properly. Due to the limited availability of homograft valves in Japan, the indications for their use are different from those in other countries. The first indication is active infective endocarditis in the aortic valve position, especially infection surrounding artificial implants. Another indication is for reconstruction of the right ventricular outflow tract during pulmonary autografting. Finally, aortic valve replacement in young women of childbearing age who wish become pregnant is an accepted indication. Since 1992, cryopreserved homograft valves have been used in Japan, and the number of surgeries performed with them has gradually increased. While efforts have been made to expand the homograft bank system in some areas, the supply remains insufficient. Because the demand for homografts is high, it is extremely important to establish a nationwide tissue bank system as soon as possible.
如果植入得当，冷冻保存的主动脉同种异体移植瓣膜是最可靠的无支架生物假体之一。由于日本同种异体移植瓣膜的供应有限，其使用指征与其他国家不同。首要指征是主动脉瓣位置的活动性感染性心内膜炎，尤其是人工植入物周围的感染。另一个指征是在自体肺动脉移植期间重建右心室流出道。最后，对于希望怀孕的育龄年轻女性进行主动脉瓣置换也是一个公认的指征。自1992年以来，冷冻保存的同种异体移植瓣膜已在日本使用，使用它们进行的手术数量逐渐增加。虽然在一些地区已努力扩大同种异体移植库系统，但供应仍然不足。由于对同种异体移植的需求很高，尽快建立全国性的组织库系统极其重要。
