Caron F
Hôpital universitaire Charles-Nicolle 76031 Rouen.
Rev Prat. 2001 Mar 31;51(6):620-7.
Acute infective endocarditis are due to highly virulent microorganisms, such as Staphylococcus aureus, able to invade normal endocardium, causing fulminant local damages (valvular destruction) as well as general damages (sepsis, metastasis), so that clinical manifestations are usually dramatic. Empirical antimicrobial therapy must be given immediately, using combinations active against the most commonly encountered pathogens. Other treatments are frequently necessary: medical therapy for heart failure, surgery of valvular reconstruction or replacement, respiratory assistance and other supportive measures. Such management requires cooperation of several disciplines.
急性感染性心内膜炎是由高毒力微生物引起的，如金黄色葡萄球菌，它能够侵袭正常的心内膜，导致严重的局部损害（瓣膜破坏）以及全身损害（败血症、转移），因此临床表现通常很严重。必须立即给予经验性抗菌治疗，使用对最常见病原体有效的联合用药。通常还需要其他治疗：心力衰竭的药物治疗、瓣膜重建或置换手术、呼吸支持及其他支持措施。这种治疗需要多个学科的协作。
