肠炎沙门氏菌鼠伤寒血清型和肠炎血清型减毒活疫苗株对无菌猪的毒力。
The virulence for gnotobiotic pigs of live attenuated vaccine strains of Salmonella enterica serovars Typhimurium and Enteritidis.
作者信息
Barrow P A, Page K, Lovell M A
机构信息
Institute for Animal Health, Compton Laboratory, Compton, Berkshire, RG20 7NN, Newbury, UK.
出版信息
Vaccine. 2001 May 14;19(25-26):3432-6. doi: 10.1016/s0264-410x(01)00065-2.
Abstract
Gnotobiotic pigs were inoculated orally with wild-type or defined aroA or cya crp vaccine strains of Salmonella enterica serovars Typhimurium and S. Enteritidis. The parental strains were virulent, inducing severe diarrhoea, dehydration and systemic disease. The cya crp mutant was also highly virulent whereas the aroA strains were attenuated.
摘要
将无菌猪经口接种肠炎沙门氏菌鼠伤寒血清型和肠炎血清型的野生型或特定aroA或cya crp疫苗株。亲本菌株具有毒性，可引发严重腹泻、脱水和全身性疾病。cya crp突变体也具有高毒性，而aroA菌株则减毒。
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