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Identification and characterization of novel superantigens from Streptococcus pyogenes.
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Superantigenic activity of emm3 Streptococcus pyogenes is abrogated by a conserved, naturally occurring smeZ mutation.
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Involvement of streptococcal mitogenic exotoxin Z in streptococcal toxic shock syndrome.
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Host-parasite factors in group A streptococcal infections. Pyrogenic and other effects of immunologic distinct exotoxins related to scarlet fever toxins.
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Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes.
J Mol Biol. 2000 May 26;299(1):157-68. doi: 10.1006/jmbi.2000.3725.
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The streptococcal superantigen SMEZ exhibits wide allelic variation, mosaic structure, and significant antigenic variation.
J Exp Med. 2000 May 15;191(10):1765-76. doi: 10.1084/jem.191.10.1765.
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Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors.
EMBO J. 1999 Jan 4;18(1):9-21. doi: 10.1093/emboj/18.1.9.
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Identification and characterization of novel superantigens from Streptococcus pyogenes.
J Exp Med. 1999 Jan 4;189(1):89-102. doi: 10.1084/jem.189.1.89.
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Streptococcal pyrogenic exotoxin A (SPE A) superantigen induced production of hematopoietic cytokines, IL-12 and IL-13 by human peripheral blood mononuclear cells.
Microb Pathog. 1997 Nov;23(5):265-72. doi: 10.1006/mpat.1997.0155.
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Differential induction of Th1 versus Th2 cytokines by group A streptococcal toxic shock syndrome isolates.
Infect Immun. 1997 Dec;65(12):5209-15. doi: 10.1128/iai.65.12.5209-5215.1997.
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Cytokines in streptococcal infections. An opening lecture.
Adv Exp Med Biol. 1997;418:869-79. doi: 10.1007/978-1-4899-1825-3_206.
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Superantigens but not mitogens are capable of inducing upregulation of E-selectin ligands on human T lymphocytes.
Exp Dermatol. 1997 Aug;6(4):161-6. doi: 10.1111/j.1600-0625.1997.tb00200.x.
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