Her C
Department of Family Medicine, University of Wisconsin Medical School, Madison 53715-1896, USA.
Am Fam Physician. 2001 May 1;63(9):1776-82.
Because of a documented increased incidence, nasopharyngeal cancer should be considered when signs or symptoms of ear, nose and throat disease are present in patients from southern China (in particular, Hong Kong and the province of Guangdong) or Southeast Asia. Environmental factors, the Epstein-Barr virus and genetic factors have been associated with the development of nasopharyngeal cancer. Patients with this malignancy most often present with a cervical mass from metastatic spread to a lymph node. Other possible presentations include ipsilateral serous otitis, hearing loss, nasal obstruction, frank epistaxis, purulent or bloody rhinorrhea, and facial neuropathy or facial nerve palsies. Radiotherapy is often curative. The addition of chemotherapy has produced high response rates in local and regionally advanced disease.
鉴于有记录显示鼻咽癌发病率上升，当来自中国南方（特别是香港和广东省）或东南亚的患者出现耳鼻喉疾病的体征或症状时，应考虑鼻咽癌。环境因素、爱泼斯坦-巴尔病毒和遗传因素与鼻咽癌的发生有关。患有这种恶性肿瘤的患者最常表现为因转移至淋巴结而出现颈部肿块。其他可能的表现包括同侧浆液性中耳炎、听力丧失、鼻塞、鼻出血、脓性或血性鼻漏以及面部神经病变或面神经麻痹。放疗通常可治愈。化疗的加入使局部和区域晚期疾病的缓解率很高。
