Fuso L, Maiolo C, Tramaglino L M, Benedetto R T, Russo A R, Spadaro S, Pagliari G
Respiratory Physiology Department, Catholic University, Rome, Italy.
Sarcoidosis Vasc Diffuse Lung Dis. 2001 Mar;18(1):85-90.
A 53-year-old man was evaluated for snoring, dysphagia for solid foods and difficulty of breathing and a polysomnographic recording was consistent with a diagnosis of obstructive sleep apnoea syndrome (OSAS). A flexible fiberoptic bronchoscopy (FFB) showed the presence of a nodular lesion of the posterior ventral surface of the tongue strictly connected to the left lateral border of the epiglottis. The biopsy specimen taken from the lesion was consistent with sarcoidosis. No involvement of pulmonary parenchyma, lymph nodes or other organs was recognized. After two months of steroid treatment, symptoms disappeared and resolution of the nodular lesion at the FFB and normalization of the polysomnographic recording were observed. This is the first report of orolaryngeal sarcoidosis associated with OSAS as the only clinical presentation of the disease.
一名53岁男性因打鼾、固体食物吞咽困难及呼吸费力接受评估,多导睡眠图记录结果符合阻塞性睡眠呼吸暂停综合征(OSAS)的诊断。纤维支气管镜检查(FFB)显示舌后腹面存在一个结节性病变,与会厌左侧缘紧密相连。取自该病变的活检标本符合结节病表现。未发现肺实质、淋巴结或其他器官受累。经过两个月的类固醇治疗,症状消失,FFB检查显示结节性病变消退,多导睡眠图记录恢复正常。这是首例以OSAS为唯一临床表现的口咽结节病报告。