Higashita R, Ichikawa S, Ban T, Suda Y, Hayashi K, Takeuchi Y
Department of Cardiovascular Surgery, Tokyo Women's Medical University Daini Hospital, 2-1-10 Nishi-Ogu, Arakawa-ku, Tokyo 116-8567, Japan.
Jpn J Thorac Cardiovasc Surg. 2001 Apr;49(4):258-60. doi: 10.1007/BF02913527.
We present a rare case of a synchronous primary lung cancer adjacent to a hamartoma. A 71-year-old woman was admitted with congestive heart failure due to acute myocardial infarction. A chest radiogram on admission showed pulmonary edema with a tumor shadow in the right upper lung field. Because histological diagnosis was not obtained preoperatively, a wedge resection of the lung was conducted using video-assisted thoracoscopic surgery. The histopathological examination confirmed the coexistence of an adenocarcinoma with a chondromatous hamartoma. Right upper lobectomy was performed followed by excision of the mediastinal lymph nodes. Although hamartoma is generally considered to be a benign neoplasm, there have been several reports of increased risk to lung cancer in patients with a chondromatous hamartoma. Therefore, we recommend that patients with a hamartoma should be submitted to a complete evaluation and to regular follow-up, considering the risk to associated synchronous malignancy.
我们报告一例罕见的与错构瘤相邻的同步原发性肺癌病例。一名71岁女性因急性心肌梗死并发充血性心力衰竭入院。入院时胸部X光片显示肺水肿，右上肺野有肿瘤阴影。由于术前未获得组织学诊断，遂采用电视辅助胸腔镜手术进行肺楔形切除术。组织病理学检查证实为腺癌与软骨瘤性错构瘤并存。随后进行了右上叶切除术及纵隔淋巴结清扫术。尽管错构瘤通常被认为是良性肿瘤，但已有数篇报道称软骨瘤性错构瘤患者患肺癌的风险增加。因此，考虑到相关同步恶性肿瘤的风险，我们建议对错构瘤患者进行全面评估并定期随访。
