Chalker J
Save the Children Fund (United Kingdom), Viet Nam.
Bull World Health Organ. 2001;79(4):313-20. Epub 2003 Jul 2.
To improve the use and dosage of antibiotics prescribed at Commune Health Stations in Viet Nam, and in so doing find out whether antibiotic dosage can be easily and reliably measured as a drug-use indicator.
All commune health workers from the 217 commune health stations in Hai Phong Province, Viet Nam, were enlisted over an 18-month study period during 1994-96. The study design was a longitudinal time series, with each new district baseline acting as a rolling control. Each health station was monitored monthly by district supervisors. Two formal evaluations by doctors external to the study were compared with the supervisors' results. Basic medical equipment was provided three times over nine months, conditional on improvements in prescribing practices and adequate supervision of prescribing practices.
The supervisors' data showed that the percentage of encounters in which a patient was prescribed an antibiotic decreased from over 65% to around 45%. When antibiotics were given, the percentage of patients who received an adequate dose increased from under 30% to 98%. These changes were stable for 17 months after the intervention stopped.
Such initiatives require the active collaboration of health personnel and civic leaders at every level. Conditional equipment donation was shown to be effective. A simple indicator measuring adequacy of antibiotic dose can be an effective tool to improve the use of antibiotics in a sustainable way.
改善越南公社卫生站抗生素的使用情况和剂量,并以此查明抗生素剂量作为用药指标是否能够轻松且可靠地进行测量。
在1994年至1996年为期18个月的研究期间,招募了越南海防省217个公社卫生站的所有公社卫生工作者。研究设计为纵向时间序列,每个新区基线作为滚动对照。地区监督员每月对每个卫生站进行监测。将研究外部医生进行的两次正式评估与监督员的结果进行比较。在九个月内分三次提供基本医疗设备,条件是处方开具做法有所改进且对处方开具做法有充分监督。
监督员的数据显示,开具抗生素处方的患者就诊百分比从超过65%降至约45%。使用抗生素时,接受适当剂量的患者百分比从不到30%增至98%。干预措施停止后,这些变化持续了17个月。
此类举措需要各级卫生人员和公民领袖的积极合作。有条件的设备捐赠被证明是有效的。一个衡量抗生素剂量是否适当的简单指标可以成为以可持续方式改善抗生素使用的有效工具。