Scala E, Giani M, Pirrotta L, Guerra E C, Cadoni S, Girardelli C R, De Pità O, Puddu P
Dept. of Immunodermatology, Allergy & Clinical Immunology, Istituto Dermopatico dell'Immacolata, I.D.I.-IRCCS, Rome, Italy.
Eur J Dermatol. 2001 May-Jun;11(3):249-50.
Anisakis simplex (AS), a fish and cephalopodes parasite, may cause allergic reactions in humans on eating and/or handling contaminated fish. We present a case of occupational hypersensitivity to AS in a woman employed in a frozen-fish factory. She showed both generalised urticarial rash and asthmatic symptoms after work place exposure. All these symptoms immediately disappeared after work place exposure was ceased. The presence of a positive skin prick test and high specific IgE values confirmed a hypersensitivity to anisakis. This is the first case reported of both occupational generalised urticaria and allergic airborne asthma due to AS in the same patient. We suggest that AS could be an important cause of occupational asthma and/or urticaria in the fish industry.
简单异尖线虫（AS）是一种鱼类和头足类寄生虫，人类在食用和/或处理受污染的鱼类时可能会引发过敏反应。我们报告了一例在冷冻鱼厂工作的女性对AS的职业性过敏病例。她在工作场所接触后出现了全身性荨麻疹皮疹和哮喘症状。停止工作场所接触后，所有这些症状立即消失。皮肤点刺试验呈阳性以及特异性IgE值高证实了对异尖线虫过敏。这是首例报告的同一患者因AS导致职业性全身性荨麻疹和过敏性气源性哮喘的病例。我们认为AS可能是鱼类加工行业职业性哮喘和/或荨麻疹的重要病因。
