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喉气管吻合术:初次手术及修正手术

Laryngotracheal anastomosis: primary and revised procedures.

作者信息

Wolf M, Shapira Y, Talmi Y P, Novikov I, Kronenberg J, Yellin A

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, Chaim Sheba Medical Center, Tel-Hashomer, and Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

Laryngoscope. 2001 Apr;111(4 Pt 1):622-7. doi: 10.1097/00005537-200104000-00012.

Abstract

OBJECTIVES

Acquired upper airway stenosis is usually associated with a complex of pathological conditions at the high tracheal and the subglottic levels. Reported reconstructive techniques include widening by incorporation of grafts, segmental resection, and anastomosis or combined procedures. The management of recurrent stenosis after reconstructive surgery is a major challenge and has rarely been discussed in the literature. The purposes of the present study are to compare the clinical course of primary versus revised reconstructive procedures and to analyze the effect of age, diabetes, chronic lung disease, grading of stenosis, extent of resection, and revised procedures on the operative rate of success.

STUDY DESIGN

A cohort study in a tertiary referral medical center.

METHODS

The clinical course of 23 consecutive patients undergoing laryngotracheal anastomosis was studied comparing a group of 13 primary with 10 revision procedures. Seventeen patients underwent cricotracheal and six patients thyrotracheal anastomoses. All patients but one were tracheotomized before the definitive reconstructive procedure. Suprahyoid release was routinely performed except for two cases, and only one patient required sternotomy. The Wilcoxon test was used to examine the relationship between preoperative clinical parameters and the postoperative success (i.e., airway patency).

RESULTS

Twenty-two of 23 patients (95.6%) had successful decannulation. Four patients required a revision procedure because of repeat stenosis at the site of the anastomosis (2) or distal tracheal malacia (2). Residual airway stenosis of less than 50% was noted in six patients, although only three complained of dyspnea during daily-activity exertion. There was no associated mortality. Complications included subcutaneous emphysema (4), granulation tissue formation (3), pneumonia (2), cardiac arrhythmia (2), and one each of pneumomediastinum, neck hematoma, and urosepsis. Protracted aspirations were noted in one patient who had revision surgery. Age was the only parameter that correlated with postoperative airway patency (P <.07), whereas the presence of chronic obstructive lung disease and diabetes, grade of stenosis, type of surgery, and revision surgery were found to be insignificant.

CONCLUSIONS

The clinical course of laryngotracheal anastomosis in primary and revised procedures was similar in our group of patients. The operation can be performed safely, with an expected high rate of success and acceptable morbidity.

摘要

目的

获得性上气道狭窄通常与高位气管和声门下水平的一系列病理状况相关。报道的重建技术包括通过植入移植物进行加宽、节段性切除、吻合术或联合手术。重建手术后复发性狭窄的处理是一项重大挑战,且在文献中很少被讨论。本研究的目的是比较初次与再次重建手术的临床过程,并分析年龄、糖尿病、慢性肺病、狭窄分级、切除范围和再次手术对手术成功率的影响。

研究设计

在一家三级转诊医疗中心进行的队列研究。

方法

对连续23例行喉气管吻合术的患者的临床过程进行研究,比较13例初次手术患者与10例再次手术患者。17例患者行环状气管吻合术,6例患者行甲状腺气管吻合术。除1例患者外,所有患者在确定性重建手术前均行气管切开术。除2例患者外,均常规行舌骨上松解术,仅1例患者需要行胸骨切开术。采用Wilcoxon检验来检查术前临床参数与术后成功(即气道通畅)之间的关系。

结果

23例患者中有22例(95.6%)成功拔管。4例患者因吻合口部位再次狭窄(2例)或远端气管软化(2例)需要再次手术。6例患者存在残余气道狭窄,狭窄程度小于50%,尽管只有3例患者在日常活动时诉有呼吸困难。无相关死亡病例。并发症包括皮下气肿(4例)、肉芽组织形成(3例)、肺炎(2例)、心律失常(2例),以及纵隔气肿、颈部血肿和泌尿道感染各1例。1例接受再次手术的患者出现长期误吸。年龄是唯一与术后气道通畅相关的参数(P <.07),而慢性阻塞性肺病和糖尿病的存在、狭窄分级、手术类型和再次手术被发现无显著意义。

结论

在我们的患者组中,初次和再次手术的喉气管吻合术临床过程相似。该手术可以安全进行,成功率预期较高,发病率可接受。

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