George Mercy, Lang Florian, Pasche Philippe, Monnier Philippe
Department of Otorhinolaryngology and Head and Neck Surgery, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.
Eur Arch Otorhinolaryngol. 2005 Aug;262(8):609-15. doi: 10.1007/s00405-004-0887-9. Epub 2005 Jan 25.
The purpose was to evaluate the outcome following the surgical management of a consecutive series of 26 adult patients with laryngotracheal stenosis of varied etiologies in a tertiary care center. Of the 83 patients who underwent surgery for laryngotracheal stenosis in the Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital of Lausanne, Switzerland, between 1995 and 2003, 26 patients were adults (> or = 16 years) and formed the group that was the focus of this study. The stenosis involved the trachea (20), subglottis (1), subglottis and trachea (2), glottis and subglottis (1) and glottis, subglottis and trachea (2). The etiology of the stenosis was post-intubation injury ( n = 20), infiltration of the trachea by thyroid tumor ( n = 3), seeding from a laryngeal tumor at the site of the tracheostoma ( n = 1), idiopathic progressive subglottic stenosis ( n = 1) and external laryngeal trauma ( n = 1). Of the patients, 20 underwent tracheal resection and end-to-end anastomosis, and 5 patients had partial cricotracheal resection and thyrotracheal anastomosis. The length of resection varied from 1.5 to 6 cm, with a median length of 3.4 cm. Eighteen patients were extubated in the operating room, and six patients were extubated during a period of 12 to 72 h after surgery. Two patients were decannulated at 12 and 18 months, respectively. One patient, who developed anastomotic dehiscence 10 days after surgery, underwent revision surgery with a good outcome. On long-term outcome assessment, 15 patients achieved excellent results, 7 patients had a good result and 4 patients died of causes unrelated to surgery (mean follow-up period of 3.6 years). No patient showed evidence of restenosis. The excellent functional results of cricotracheal/tracheal resection and primary anastomosis in this series confirm the efficacy and reliability of this approach towards the management of laryngotracheal stenosis of varied etiologies. Similar to data in the literature, post-intubation injury was the leading cause of stenosis in our series. A resection length of up to 6 cm with laryngeal release procedures (when necessary) was found to be technically feasible.
目的是评估在一家三级医疗中心对连续26例病因各异的成年喉气管狭窄患者进行手术治疗后的结果。在瑞士洛桑大学医院耳鼻咽喉头颈外科,1995年至2003年间有83例患者接受了喉气管狭窄手术,其中26例为成年人(≥16岁),构成了本研究的重点群体。狭窄累及气管(20例)、声门下(1例)、声门下和气管(2例)、声门和声门下(1例)以及声门、声门下和气管(2例)。狭窄的病因包括插管后损伤(n = 20)、甲状腺肿瘤侵犯气管(n = 3)、气管造口处喉肿瘤播散(n = 1)、特发性进行性声门下狭窄(n = 1)和喉外部创伤(n = 1)。这些患者中,20例行气管切除端端吻合术,5例行部分环状气管切除和甲状腺气管吻合术。切除长度从1.5至6 cm不等,中位长度为3.4 cm。18例患者在手术室拔管,6例患者在术后12至72小时内拔管。2例患者分别在术后12个月和18个月拔管。1例患者术后10天发生吻合口裂开,接受修复手术后效果良好。在长期结果评估中,15例患者取得优异结果,7例患者结果良好,4例患者死于与手术无关的原因(平均随访期3.6年)。无患者出现再狭窄迹象。本系列中环状气管/气管切除及一期吻合术的优异功能结果证实了该方法治疗各种病因喉气管狭窄的有效性和可靠性。与文献数据相似,插管后损伤是本系列狭窄的主要原因。发现切除长度达至6 cm并在必要时行喉部松解术在技术上是可行的。