Zhang Y, Huang H, Lian L
Chinese Academy of Medical Science, Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730.
Zhonghua Fu Chan Ke Za Zhi. 1999 Sep;34(9):544-6.
To analyse the relationship between endometriosis and epithelial ovarian cancer.
We analyzed retrospectively the 20 cases associated with endometriosis in 371 cases of epithelial ovarian cancer, and these 20 cases were also compared with the left 351 cases not associated with endometriosis(including endomtriod carcinoma 38 cases and clear cell carcinoma 39 cases).
Among 20 cases, endomtriod carcinoma and clear cell carcinoma were most frequently associated with endometriosis, with 11 cases and 7 cases respectively, there was also 1 case of gland carcinoma and 1 case of serous papillary carcinoma. Cases of carcinomas associated with endometriosis had higher pathological grade and 5-year survival probability (Kaplan-Meier method) than those cases not associated with endometriosis.
There is a close relationship between endometriosis and ovarian endomtriod carcinoma and clear cell carcinoma, the malignant transformation of endometriosis foci may be an important origin of them. Drug therapy is recommended for endomtriosis after the operation. In the treatment of endomtriod carcinoma and clear cell carcinoma, progestin can be used as an accessory method.
分析子宫内膜异位症与上皮性卵巢癌之间的关系。
回顾性分析371例上皮性卵巢癌中与子宫内膜异位症相关的20例病例，并将这20例病例与另外351例不伴有子宫内膜异位症的病例（包括子宫内膜样癌38例和透明细胞癌39例）进行比较。
20例病例中，子宫内膜样癌和透明细胞癌与子宫内膜异位症关联最为常见，分别为11例和7例，还有1例腺管癌和1例浆液性乳头状癌。与子宫内膜异位症相关的癌病例比不伴有子宫内膜异位症的病例具有更高的病理分级和5年生存概率（Kaplan-Meier法）。
子宫内膜异位症与卵巢子宫内膜样癌和透明细胞癌之间存在密切关系，子宫内膜异位症病灶的恶变可能是它们的重要起源。术后建议对子宫内膜异位症进行药物治疗。在子宫内膜样癌和透明细胞癌的治疗中，孕激素可作为辅助方法使用。
