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滑液对边界润滑的演示。

Demonstration of boundary lubrication by synovial fluid.

作者信息

Reimann I, Stougaard J, Northeved A, Johnsen S J

出版信息

Acta Orthop Scand. 1975 Apr;46(1):1-10. doi: 10.3109/17453677508989186.

DOI:10.3109/17453677508989186
PMID:1136724
Abstract

An account is given of an oscillatory rotating friction measurement apparatus which can be used for demonstration of boundary lubrication by synovial fluid when rubber and glass are employed as rubbing surfaces. A technical description of the apparatus is given. The greatest importance is placed on getting the apparatus to demonstrate reproducible results when saline and normal bovine synovial fluid are used as lubricant. The greatest variations are caused by differences in the cleaning of the rubber and in its tension. On the basis of bovine synovial fluid from ten different hock joints investigations were made of individual variations and changes occurring during storage at 4 degrees C. The individual variations were found to be of no importance; a decrease in the lubricating effect was observed only after storage for two months. Addition of trypsin confirmed that boundary lubrication by synovial fluid can be related to the protein component. The conclusion is that the apparatus is considered suitable for clinical investigations of boundary lubrication in connection with different joint diseases.

摘要

介绍了一种振荡旋转摩擦测量装置,当以橡胶和玻璃作为摩擦表面时,该装置可用于演示滑液的边界润滑。给出了该装置的技术说明。最重要的是使该装置在用盐水和正常牛滑液作为润滑剂时能产生可重复的结果。最大的差异是由橡胶清洁程度及其张力的不同所引起的。基于来自十个不同跗关节的牛滑液,研究了在4℃储存期间发生的个体差异和变化。发现个体差异并不重要;仅在储存两个月后才观察到润滑效果下降。添加胰蛋白酶证实滑液的边界润滑可能与蛋白质成分有关。结论是该装置被认为适用于与不同关节疾病相关的边界润滑的临床研究。

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Demonstration of boundary lubrication by synovial fluid.滑液对边界润滑的演示。
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J Mater Sci Mater Med. 2012 May;23(5):1323-30. doi: 10.1007/s10856-012-4603-9. Epub 2012 Mar 10.
2
Boundary lubrication by lubricin is mediated by O-linked beta(1-3)Gal-GalNAc oligosaccharides.润滑素介导的边界润滑由O-连接的β(1-3)半乳糖- N -乙酰半乳糖胺寡糖介导。
Glycoconj J. 2001 Oct;18(10):807-15. doi: 10.1023/a:1021159619373.