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[Comparative study on the effect of gossypol and T7 on human spermatozoa ATPase activity].

作者信息

Wu F, Zhang Z, Ye W, Qian X

机构信息

Institute of Basic Medical Sciences, Beijing 100005.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1998 Aug;20(4):267-70.

PMID:11367690
Abstract

OBJECTIVE

A comparative study was carried out on the effect of two kinds of male contraceptive drugs, gossypol and the abstract of tripterygium wilfordii T7, on the human spermatozoa ATPase activity.

METHODS

The specific activity of total ATPase and Na-K ATPase of spermatozoa was assayed in this experiment.

RESULTS

(1) The effect of gossypol on the human spermatozoa ATPase activity is inhibitory and concentration-dependent; and (2) The abstract of tripterygium wilfodii T7 has no effect on the human spermatozoa ATPase activity.

CONCLUSIONS

The antifertility effects of gossypol and T7 are different.

摘要

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