Bergdahl J, Bergdahl M
Department of Psychology, Umeå University, Sweden.
Acta Odontol Scand. 2001 Apr;59(2):104-10. doi: 10.1080/000163501750157270.
Patients with symptoms allegedly caused by abnormal sensitivity to dental fillings and/or to electromagnetic fields and other environmental factors frequently report oral complaints. Forty-four consecutive patients with these symptoms were studied. The aim was to investigate whether unstimulated salivary flow rate was associated with Candida, symptoms, disease, medication, age, sex, anxiety, depression, and stress. Furthermore, the aim was to compare the level of anxiety, depression, and stress in these patients with an age- and sex-matched control group. Fifty percent had no or low flow rate from the minor salivary glands. Candida pseudohyphae were found in 50% of the patients. Hypothyroidism and/or intake of thyroid hormones, headache, fatigue, and age were negatively associated with unstimulated salivary flow rate, and dizziness was positively associated. Unstimulated salivary flow rate was positively associated with stimulated salivary flow rate and flow rate from the minor salivary glands. Burning mouth and subjective oral dryness were reported by 48%, and 46%, respectively. The patients were more anxious, stressed, and especially more depressed than the control group. Unstimulated salivary flow rate was negatively associated with state anxiety. Measurement of salivary flow rate is important in patients with environmental illness and can be used in combination with other measurements as a diagnostic tool.
据称因对牙科填充物和/或电磁场及其他环境因素异常敏感而出现症状的患者经常报告口腔不适。对连续44例有这些症状的患者进行了研究。目的是调查非刺激性唾液流速是否与念珠菌、症状、疾病、用药、年龄、性别、焦虑、抑郁和压力有关。此外，目的是将这些患者的焦虑、抑郁和压力水平与年龄和性别匹配的对照组进行比较。50%的患者小唾液腺无分泌或分泌率低。50%的患者发现念珠菌假菌丝。甲状腺功能减退和/或甲状腺激素摄入、头痛、疲劳和年龄与非刺激性唾液流速呈负相关，头晕与之呈正相关。非刺激性唾液流速与刺激性唾液流速和小唾液腺分泌率呈正相关。分别有48%和46%的患者报告有灼口和主观口腔干燥。这些患者比对照组更焦虑、压力更大，尤其是更抑郁。非刺激性唾液流速与状态焦虑呈负相关。测量唾液流速对环境疾病患者很重要，可与其他测量方法结合用作诊断工具。
