Suuronen R, Kallela I, Lindqvist C
Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital, Helsinki, Finland.
J Craniomaxillofac Trauma. 2000 Spring;6(1):19-27; discussion 28-30.
The use of bioabsorbable materials in craniomaxillofacial surgery began a new era in fracture fixation. The purpose of this paper is to review the historical perspectives and the current concept of bioresorbable materials in fracture fixation.
The authors review the biochemistry and clinical characteristics of bioabsorbable polymers--polylactic acid (PLA), polyglycolic acid (PGA), polydioxanone (PDS), and their copolymers. Their use and clinical perspectives by the Helsinki (authors') group and other study groups are presented.
These materials have proven to be safe in clinical applications. When manufactured with current technology, they are easy to handle. Economically, they are nearly equal to similar metal devices. The materials have met clinical success throughout the world, first in orthognathic surgery, followed by treatment of fractures of the upper facial skeleton and the mandible. Today, most maxillofacial fractures and osteotomies may be adequately fixed with bioabsorbable materials.
生物可吸收材料在颅颌面外科手术中的应用开启了骨折固定的新纪元。本文旨在回顾生物可吸收材料在骨折固定方面的历史观点和当前概念。
作者回顾了生物可吸收聚合物——聚乳酸（PLA）、聚乙醇酸（PGA）、聚二氧六环酮（PDS）及其共聚物的生物化学和临床特性。介绍了赫尔辛基（作者）团队及其他研究团队对它们的使用情况和临床观点。
这些材料在临床应用中已被证明是安全的。采用当前技术制造时，它们易于操作。在经济方面，它们与类似的金属器械近乎相当。这些材料在全球范围内均取得了临床成功，首先应用于正颌外科手术，随后用于治疗上颌面部骨骼和下颌骨骨折。如今，大多数颌面骨折和截骨术都可用生物可吸收材料进行充分固定。
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