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家兔血清酯酶遗传学。III. Est-2基因座上的第三个等位基因。

Serum esterase genetics in rabbits. III. A third allele on the Est-2 locus.

作者信息

van Zutphen L F, den Bieman M G

出版信息

Biochem Genet. 1975 Feb;13(1-2):19-28. doi: 10.1007/BF00486003.

DOI:10.1007/BF00486003
PMID:1137564
Abstract

A fast-migrating F' zone of the prealbumin serum esterase system of rabbits is demonstrated in low frequency in the breed Vienna White (stock Cpb:VW). Evidence is given that this zone is controlled by a third allele of the Est-2 locus. The zymotypic expression of this allele (Est-2-F') shows codominance in combination with the Est-2-F allele and complete dominance in combination with the Est-2-F' allele. In contradistinction to the F zones of the Est-2-F allele, the F' zone possesses no atropinesterase activity.

摘要

在维也纳白兔（品系Cpb:VW）品种中，兔前清蛋白血清酯酶系统的一个快速迁移的F'区出现频率较低。有证据表明，该区域由Est-2位点的第三个等位基因控制。该等位基因（Est-2-F'）的酶型表达与Est-2-F等位基因结合时表现为共显性，与Est-2-S等位基因结合时表现为完全显性。与Est-2-F等位基因的F区不同，F'区不具有阿托品酯酶活性。

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引用本文的文献

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2
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本文引用的文献

1
PROTEINS AND ISOZYMES OF ESTERASES AND CHOLINESTERASES FROM SERA OF DIFFERENT SPECIES.不同物种血清中酯酶和胆碱酯酶的蛋白质及同工酶
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Responses of esterase 6 alleles of Drosophila melanogaster and D. simulans to selection in experimental populations.黑腹果蝇和拟暗果蝇酯酶6等位基因在实验种群中对选择的反应。
Genetics. 1966 Mar;53(3):371-87. doi: 10.1093/genetics/53.3.371.
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Esterase heterogeneity: dynamics of a polymorphism.酯酶异质性：一种多态性的动态变化
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Atropinesterase and cocainesterase of rabbit serum: localization of the enzyme activity in isozymes.兔血清中的阿托品酯酶和可卡因酯酶：酶活性在同工酶中的定位
Science. 1970 Jan 9;167(3915):200-2. doi: 10.1126/science.167.3915.200.
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Ann N Y Acad Sci. 1968 Jun 14;151(1):531-9. doi: 10.1111/j.1749-6632.1968.tb11912.x.
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Protein polymorphism as a phase of molecular evolution.蛋白质多态性作为分子进化的一个阶段。
Nature. 1971 Feb 12;229(5285):467-9. doi: 10.1038/229467a0.
8
Evidence that enzyme polymorphisms are not selectively neutral.
Nat New Biol. 1972 Jun 7;237(75):170-1. doi: 10.1038/newbio237170a0.
9
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10
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Biochem Genet. 1974 Oct;12(4):309-26. doi: 10.1007/BF00485951.