Platas G, Acero J, Borkowski J A, González V, Portal M A, Rubio V, Sánchez-Ballesteros J, Salazar O, Peláez F
Centro de Investigación Básica, Natural Products Drug Discovery, Merck Sharp & Dohme Research Laboratories, Merck Sharp, & Dohme de España, S. A. Josefa Valcárcel 38. 28027, Madrid, Spain.
Curr Microbiol. 2001 Jul;43(1):43-50. doi: 10.1007/s002840010258.
A Simple Tandem Repeat sequence of 11 nucleotides has been found in the ITS1 region of the rDNA of members of Order Xylariales. The number of repetitions detected ranged from one to six, and they could be found in pure tandem or interspersed. The same core sequences have also been found in DNA from other organisms, although usually not repeated in tandem. These repetitions could have been generated by slipped strand mispairing. The presence of this sequence increases the normal rate of divergence in the ITS1 of the Xylariales. The phylogenetic implications of the presence of this sequence in the molecular taxonomy of Xylariales are also discussed.
在炭角菌目成员的核糖体DNA的ITS1区域中发现了一个由11个核苷酸组成的简单串联重复序列。检测到的重复次数从1到6不等，它们可以以纯串联或散布的形式存在。在其他生物体的DNA中也发现了相同的核心序列，尽管通常不是串联重复的。这些重复可能是由滑链错配产生的。该序列的存在增加了炭角菌目ITS1的正常分歧率。本文还讨论了该序列在炭角菌目分子分类学中的系统发育意义。
