Therasse E, Côté G, Oliva V L, Cusson J R, Wistaff R, Nguyen P V, Bui B T, Perreault P, Lamarre L, Soulez G
Depts of Radiology, Centre Hospitalier de l'Université de Montréal (CHUM), 3840 St Urbain St, Montreal, Quebec, Canada.
Radiology. 2001 Jun;219(3):655-62. doi: 10.1148/radiology.219.3.r01jn19655.
To evaluate the long-term clinical and hemodynamic effectiveness of aortic stent placement in cases of failure of intended infrarenal percutaneous transluminal aortic angioplasty (PTAA).
Fifty-three patients who underwent technically successful PTAA were compared with 24 patients who underwent aortic stent placement because of PTAA failure (19 patients) or ulcerated lesions (five patients) that otherwise would have been treated surgically because of the embolization hazard associated with PTAA alone. Clinical patency was defined as the absence or improvement of symptoms after the intervention. Hemodynamic patency was defined as a normal Doppler waveform in the common femoral arteries, an ankle-brachial index greater than 0.95, or the absence of a thigh-brachial pressure gradient.
Three-year clinical and hemodynamic patency rates, respectively, were 85% and 79% for PTAA and 69% and 43% for aortic stent placement. No morbidity was encountered. With use of the Cox proportional hazards model, two significant risk factors were retained for restenosis: unchanged smoking habit (P =.04) and small dilatation diameter (P =.001). Aortic stent placement, performed in patients with a smaller aortic diameter (10.3 vs. 12.7 mm for PTAA), appeared to be a predictive factor for restenosis by using univariate analysis. By using the Cox proportional hazards model, however, the restenosis rates after PTAA and aortic stent placement were not significantly different.
When aortic diameter is taken into consideration, there is no evidence that clinical outcome after secondary aortic stent placement would be poorer than technically successful PTAA.
评估在预期的肾下腹主动脉经皮腔内血管成形术(PTAA)失败的情况下,主动脉支架置入术的长期临床和血流动力学效果。
将53例技术上成功接受PTAA的患者与24例因PTAA失败(19例)或溃疡病变(5例)而接受主动脉支架置入术的患者进行比较,这些溃疡病变若仅因PTAA相关的栓塞风险,原本需手术治疗。临床通畅定义为干预后症状消失或改善。血流动力学通畅定义为股总动脉多普勒波形正常、踝臂指数大于0.95或无大腿-臂部压力梯度。
PTAA组的三年临床和血流动力学通畅率分别为85%和79%,主动脉支架置入组分别为69%和43%。未出现并发症。使用Cox比例风险模型,保留了两个再狭窄的显著危险因素:吸烟习惯未改变(P = 0.04)和扩张直径较小(P = 0.001)。主动脉支架置入术用于主动脉直径较小的患者(PTAA组为12.7 mm,主动脉支架置入组为10.3 mm),单因素分析显示这似乎是再狭窄的预测因素。然而,使用Cox比例风险模型时,PTAA和主动脉支架置入术后的再狭窄率无显著差异。
考虑主动脉直径时,没有证据表明二次主动脉支架置入术后的临床结果会比技术上成功的PTAA差。