Audet P, Therasse E, Oliva V L, Soulez G, Côté G, Wistaff R, Nguyen P V, Blair J F, Bui B T, Cusson J R
Dept of Radiology, Univ of Montreal Medical Center, Quebec, Canada.
Radiology. 1998 Nov;209(2):357-63. doi: 10.1148/radiology.209.2.9807559.
To evaluate the safety and long-term clinical and hemodynamic results of percutaneous transluminal angioplasty (PTA) of the infrarenal aorta.
During nearly 10 years, 102 patients with symptomatic infrarenal atherosclerotic aortic stenosis underwent PTA. Follow-up information was available in 92 patients (17 men, 75 women; mean age, 51.9 years). Stenosis involved the aortic bifurcation in 18 patients and only the infrarenal abdominal aorta in 74 patients. Technical success was defined as residual stenosis less than 50% or a pressure gradient less than 10 mm Hg after PTA. Clinical patency was defined as the absence or improvement of symptoms after PTA. Hemodynamic patency was defined as a normal Doppler waveform in the common femoral arteries, an ankle-brachial ratio greater than 0.95, or the absence of a thigh-brachial pressure gradient.
Technical success was achieved in 78 patients after PTA. After 10 years, primary clinical and hemodynamic patency rates were 72% and 46%, respectively. After a mean follow-up of 51 months, 15 of the 22 symptomatic recurrences were due to aortic restenosis; 11 of these were treated with repeated PTA with or without stent placement, and three eventually required aortic surgery. No morbidity was encountered.
Infrarenal aortic PTA proved to be safe and provided durable, long-term clinical improvement. In this group of relatively young patients, the clinical patency rate of PTA was equivalent to that of aortic surgery but with less morbidity.
评估经皮腔内血管成形术(PTA)治疗肾下腹主动脉的安全性以及长期临床和血流动力学结果。
在近10年中,102例有症状的肾下腹主动脉粥样硬化性狭窄患者接受了PTA治疗。92例患者(17例男性,75例女性;平均年龄51.9岁)有随访信息。18例患者的狭窄累及主动脉分叉,74例患者仅累及肾下腹主动脉。技术成功定义为PTA术后残余狭窄小于50%或压力阶差小于10 mmHg。临床通畅定义为PTA术后症状消失或改善。血流动力学通畅定义为股总动脉多普勒波形正常、踝肱指数大于0.95或不存在股肱压力阶差。
PTA术后78例患者获得技术成功。10年后,原发性临床和血流动力学通畅率分别为72%和46%。平均随访51个月后,22例症状复发患者中有15例是由于主动脉再狭窄;其中11例接受了重复PTA治疗,有或没有置入支架,3例最终需要进行主动脉手术。未发生并发症。
肾下腹主动脉PTA被证明是安全的,并能提供持久的长期临床改善。在这组相对年轻的患者中,PTA的临床通畅率与主动脉手术相当,但并发症较少。