de Vries J P P M, van Den Heuvel D A F, Vos J A, van Den Berg J C, Moll F I
Department of Vascular Surgery, St Antonius Hospital, Nieuwegein, The Netherlands.
J Vasc Surg. 2004 Feb;39(2):427-31. doi: 10.1016/j.jvs.2003.08.032.
The purpose of this study was to determine the long-term results (1-15 years) of percutaneous transluminal angioplasty (PTA) of localized atherosclerotic lesions of the infrarenal aorta.
This was a retrospective study. From January 1987 to January 2002, 69 patients underwent PTA of an isolated stenosis of the lower abdominal aorta under local anesthesia in the department of interventional radiology. All atherosclerotic lesions were hemodynamically significant, defined as a subjective report of walking distance less than one block, resting pain, or trophic changes in combination with diameter reduction of 50% or greater at duplex ultrasound scanning and angiography.
The female-male ratio of study patients was 3.6:1; mean age was 58 years. Endovascular treatment was initially technically and clinically successful in all but one patient (98%), who had a near total occlusion. No major complications were noted. Mean follow-up was 57 months (range, 6 months-15 years). At life table analysis, 5-year primary patency was 75%, and secondary patency was 97%. Twelve patients (17%) required repeat interventions because of hemodynamically significant recurrent stenosis in combination with severe clinical symptoms. Most recurrent stenoses (67%) were successfully treated with repeat endovascular procedures.
Early and long-term results of PTA (with additional stent placement) of isolated stenosis of the infrarenal aorta are good. This minimally invasive procedure is a true alternative to traditional surgical methods.
本研究的目的是确定经皮腔内血管成形术(PTA)治疗肾下腹主动脉局限性动脉粥样硬化病变的长期结果(1至15年)。
这是一项回顾性研究。1987年1月至2002年1月,69例患者在介入放射科局部麻醉下接受了下腹主动脉孤立性狭窄的PTA治疗。所有动脉粥样硬化病变在血流动力学上均具有显著意义,定义为步行距离主观报告少于一个街区、静息痛或营养改变,同时在双功超声扫描和血管造影中直径缩小50%或更多。
研究患者的男女比例为3.6:1;平均年龄为58岁。除1例几乎完全闭塞的患者外,血管内治疗最初在技术和临床上均获成功(98%)。未观察到重大并发症。平均随访57个月(范围6个月至15年)。在生命表分析中,5年的初次通畅率为75%,二次通畅率为97%。12例患者(17%)因血流动力学上显著的复发性狭窄并伴有严重临床症状而需要重复干预。大多数复发性狭窄(67%)通过重复血管内手术成功治疗。
肾下腹主动脉孤立性狭窄的PTA(附加支架置入)的早期和长期结果良好。这种微创手术是传统手术方法的真正替代方案。