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[儿童尿路病原体分离株的抗菌药物敏感性模式]

[Pattern of antimicrobial susceptibility in uropathogen isolates from children].

作者信息

Suárez V M, Suárez R C, Pérez B A, Alvarez F A, Castro S P, Rodríguez F S, Guerrero S M

机构信息

Sección de Nefrología Pediátrica, Hospital Central de Asturias, Oviedo.

出版信息

Rev Esp Quimioter. 2001 Mar;14(1):63-8.

Abstract

The bacteriological profile in children with culture-positive bacteriuria was analyzed during a 5-year period. Escherichia coli was the most common cause of urinary tract infections (57%), followed by Streptococcus faecalis (11%), Pseudomonas aeruginosa (8%), and Proteus mirabilis (6%). Results of antimicrobial susceptibility testing indicated that cephalosporins (first, second and third generation) and nitrofurantoin are the best empirical oral treatment for urinary infections in children. Fosfomycin is a valid option in some cases. In hospitalized children treatment must be initiated with a third-generation cephalosporin, and gentamicin can be added in severely ill inpatients. These treatments can be modified when microbiological results become available.

摘要

在5年期间对培养阳性菌尿症患儿的细菌学特征进行了分析。大肠埃希菌是尿路感染最常见的病因(57%),其次是粪肠球菌(11%)、铜绿假单胞菌(8%)和奇异变形杆菌(6%)。抗菌药敏试验结果表明,头孢菌素(第一代、第二代和第三代)和呋喃妥因是儿童尿路感染最佳的经验性口服治疗药物。磷霉素在某些情况下是一种有效的选择。对于住院患儿,治疗必须从第三代头孢菌素开始,对于重症住院患者可加用庆大霉素。当获得微生物学结果时,这些治疗方案可以进行调整。

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