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重症监护病房中机械通气应用的演变

Evolution in the utilization of the mechanical ventilation in the critical care unit.

作者信息

Frutos F, Alìa I, Esteban A, Anzueto A

机构信息

Intensive Care Unit, Hospital Universitario de Getafe, Carretera de Toledo Km 12,500, 28905-Getafe, Madrid, Spain.

出版信息

Minerva Anestesiol. 2001 Apr;67(4):215-22.

Abstract

Use of mechanical ventilation has increased in recent years and constitutes a major therapeutic modality in the intensive care unit (ICU). In the recent years, changes in the ventilatory modes, in the ventilatory strategies and in the weaning from mechanical ventilation have occurred. We have compared the data obtained from the Spanish ICUs in studies that were carried out in three periods of the nineties, with the aim to test whether the aforementioned innovations have modified the clinical practice. We analyzed demographic data, primary reason for mechanical ventilation, ventilatory parameters, mode of weaning and performance of tracheostomy. It was observed a decrease in the percentage of patients receiving mechanical ventilation. There was a significant trend to ventilate older patients over the course of the decade. In the mode of ventilation, we observed a significant decrease in the use of the synchronized intermittent mandatory ventilation with a increment in the use of assist-control ventilation. We did not find differences in the ventilatory settings. Concerning to weaning, over the course of the decade occurred an increase in use of pressure support ventilation and spontaneous breathing trial, being this method the most frequently used at the end of the decade. The performance of the tracheostomy has been lesser and earlier over the time. The results obtained suggest that findings from research on mechanical ventilation are incorporated into clinical practice at a very slow pace whereas the evidence obtained from the clinical trials about weaning has had a better reception.

摘要

近年来,机械通气的使用有所增加,并且是重症监护病房(ICU)的一种主要治疗方式。近年来,通气模式、通气策略以及机械通气撤机方面都发生了变化。我们比较了在九十年代三个时期开展的研究中从西班牙重症监护病房获得的数据,目的是检验上述创新是否改变了临床实践。我们分析了人口统计学数据、机械通气的主要原因、通气参数、撤机模式以及气管切开术的实施情况。观察到接受机械通气的患者百分比有所下降。在这十年间,为老年患者进行通气有显著趋势。在通气模式方面,我们观察到同步间歇指令通气的使用显著减少,辅助控制通气的使用有所增加。我们未发现通气设置方面存在差异。关于撤机,在这十年间,压力支持通气和自主呼吸试验的使用有所增加,到这十年末这种方法使用最为频繁。随着时间推移,气管切开术的实施次数减少且时间提前。所获得的结果表明,关于机械通气的研究结果在临床实践中的应用非常缓慢,而来自临床试验关于撤机的证据得到了更好的接受。

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