Okabe S, Kuriyama Y, Kawanishi Y, Yahata N, Miyazawa K, Kimura Y, Serizawa H, Ebihara Y, Ohyashiki K
First Department of Internal Medicine, Tokyo Medical University, Japan.
Leuk Lymphoma. 2001 Apr;41(3-4):461-3. doi: 10.3109/10428190109058006.
A case of marginal zone B cell lymphoma of MALT type arising in the uvula and breast is reported. The patient, a 30-year-old woman who delivered a child and lactated in 1997, was suffering from Sjögren syndrome (SS). She was diagnosed with MALT lymphoma after a biopsy of the right breast and uvula. To investigate the relationship of the delivery, lactation and MALT lymphoma, we examined the immunohistochemical analysis of hormone receptors. As a result, lymphoid cells of the breast were stained with anti-progesterone receptor antibodies in the cytoplasm. Consequently, the MALT lymphoma of the uvula appeared to be associated with SS. Moreover, hormones such as progesterone may have influenced the breast involvement of MALT lymphoma in our case.
报告了一例发生于悬雍垂和乳腺的黏膜相关淋巴组织（MALT）型边缘区B细胞淋巴瘤病例。该患者为一名30岁女性，1997年分娩并哺乳，患有干燥综合征（SS）。经右乳腺和悬雍垂活检后，她被诊断为MALT淋巴瘤。为研究分娩、哺乳与MALT淋巴瘤之间的关系，我们进行了激素受体的免疫组化分析。结果显示，乳腺的淋巴细胞在细胞质中被抗孕激素受体抗体染色。因此，悬雍垂的MALT淋巴瘤似乎与SS有关。此外，在我们的病例中，孕激素等激素可能影响了MALT淋巴瘤的乳腺受累情况。
