Sprent J
Department of Immunology, IMM4, The Scripps Research Institute, La Jolla, California 92037, USA.
Immunol Cell Biol. 2001 Jun;79(3):199-206. doi: 10.1046/j.1440-1711.2001.00999.x.
Typical T cells are long-lived resting cells. Despite their quiescent appearance, there is increasing evidence that T cells are subjected to continuous stimulation through contact with various stimuli, notably by self peptide/MHC complexes and cytokines. These stimuli keep T cells alive and also cause intermittent entry into cell cycle.
