印度不同动物物种中抗戊型肝炎病毒抗体的流行情况。
Prevalence of anti-hepatitis E virus antibodies in different Indian animal species.
作者信息
Arankalle V A, Joshi M V, Kulkarni A M, Gandhe S S, Chobe L P, Rautmare S S, Mishra A C, Padbidri V S
机构信息
Hepatitis Division, National Institute of Virology, 20-A, Dr Ambedkar Road, Pune 411001, India.
出版信息
J Viral Hepat. 2001 May;8(3):223-7. doi: 10.1046/j.1365-2893.2001.00290.x.
Prevalence of IgG antibodies to hepatitis E virus (IgG-anti-HEV) was determined among different animal species from India. Seropositivity varied from 4.4% to 6.9% in cattle, 54.6-74.4% in pigs and 2.1-21.5% in rodents. Of the 44 dogs screened, 10 were positive (22.7%). None of the 250 goat sera tested were found to be anti-HEV positive. Among rodents, over 50% serum samples collected in 1985 from Bandicota bengalensis were positive for anti-HEV antibodies. No evidence of HEV infection was obtained following experimental inoculation of an Indian strain (AKL-90) of HEV into anti-HEV negative pigs and goats. The results document varied prevalence of anti-HEV antibodies in different animal species from India and of inability of Indian pigs and goats to support replication of at least one human strain of HEV.
在印度不同动物物种中测定了戊型肝炎病毒IgG抗体（IgG-anti-HEV）的流行情况。牛的血清阳性率在4.4%至6.9%之间，猪为54.6 - 74.4%，啮齿动物为2.1 - 21.5%。在筛查的44只狗中，10只呈阳性（22.7%）。所检测的250份山羊血清均未发现抗HEV阳性。在啮齿动物中，1985年从孟加拉板齿鼠采集的血清样本中，超过50%抗HEV抗体呈阳性。将一株印度戊型肝炎病毒（AKL - 90）实验接种到抗HEV阴性的猪和山羊中后，未获得戊型肝炎病毒感染的证据。这些结果证明了印度不同动物物种中抗HEV抗体的流行情况各异，以及印度猪和山羊无法支持至少一种人类戊型肝炎病毒株的复制。
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