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家畜中的戊型肝炎病毒——流行病学及其对人类感染风险的最新情况

Hepatitis E Virus in Livestock-Update on Its Epidemiology and Risk of Infection to Humans.

作者信息

Turlewicz-Podbielska Hanna, Augustyniak Agata, Wojciechowski Jarosław, Pomorska-Mól Małgorzata

机构信息

Department of Preclinical Sciences and Infectious Diseases, Poznan University of Life Sciences, Wolynska 35, 60-637 Poznan, Poland.

VETPOL SP. Z.O.O., Grabowa 3, 86-300 Grudziądz, Poland.

出版信息

Animals (Basel). 2023 Oct 17;13(20):3239. doi: 10.3390/ani13203239.

DOI:10.3390/ani13203239
PMID:37893962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10603682/
Abstract

Hepatitis E virus (HEV) is a public health problem worldwide and an important food pathogen known for its zoonotic potential. Increasing numbers of infection cases with human HEV are caused by the zoonotic transmission of genotypes 3 and 4, mainly by consuming contaminated, undercooked or raw porcine meat. Pigs are the main reservoir of HEV. However, it should be noted that other animal species, such as cattle, sheep, goats, and rabbits, may also be a source of infection for humans. Due to the detection of HEV RNA in the milk and tissues of cattle, the consumption of infected uncooked milk and meat or offal from these species also poses a potential risk of zoonotic HEV infections. Poultry infected by avian HEV may also develop symptomatic disease, although avian HEV is not considered a zoonotic pathogen. HEV infection has a worldwide distribution with different prevalence rates depending on the affected animal species, sampling region, or breeding system.

摘要

戊型肝炎病毒(HEV)是一个全球性的公共卫生问题,也是一种重要的食源性病原体,因其具有人畜共患病潜力而闻名。由3型和4型基因型的人畜共患病传播导致的人类戊型肝炎感染病例数量不断增加,主要是通过食用受污染的、未煮熟或生的猪肉。猪是戊型肝炎病毒的主要宿主。然而,应该注意的是,其他动物物种,如牛、羊、山羊和兔子,也可能是人类的感染源。由于在牛的牛奶和组织中检测到戊型肝炎病毒RNA,食用来自这些物种的受感染生牛奶、肉类或内脏也构成了戊型肝炎人畜共患病感染的潜在风险。感染禽戊型肝炎病毒的家禽也可能出现症状性疾病,尽管禽戊型肝炎病毒不被认为是一种人畜共患病原体。戊型肝炎病毒感染在全球范围内分布,根据受影响的动物物种、采样地区或养殖系统的不同,患病率也有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/e2c14b9d4365/animals-13-03239-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/f09f79e37ec8/animals-13-03239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/a76c5b4bd362/animals-13-03239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/1e741ff05c20/animals-13-03239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/e2c14b9d4365/animals-13-03239-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/f09f79e37ec8/animals-13-03239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/a76c5b4bd362/animals-13-03239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/1e741ff05c20/animals-13-03239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f87/10603682/e2c14b9d4365/animals-13-03239-g004.jpg

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