Rietschel R L, Mathias C G, Taylor J S, Storrs F J, Sherertz E F, Pratt M, Marks J G, Maibach H I, Fransway A F, Fowler J F, DeLeo V A, Belsito D V
North American Contact Dermatitis Group and Ochsner Clinic, New Orleans, LA 70121, USA.
Am J Contact Dermat. 2001 Jun;12(2):72-6. doi: 10.1053/ajcd.2001.19630.
The interplay between the occupational environment and worker's skin can result in contact dermatitis of both irritant and allergic types. Other forms of dermatitis can also be influenced by occupational exposures.
The aim of this study is to compare the occupations and allergens of occupational contact dermatitis cases with nonoccupational contact dermatitis cases.
Diagnostic patch testing with allergens of the North American Contact Dermatitis Group and occupational coding by the National Institute for Occupational Safety and Health methods.
Of 2,889 patients referred for evaluation of contact dermatitis, 839 patients (29%) were found to have occupational contact dermatitis. Of the 839 cases deemed occupational, 455 cases (54%) were primarily allergic in nature and 270 cases (32%) were primarily irritant in nature. The remaining 14% were diagnoses other than contact dermatitis, aggravated by work. The occupation most commonly found to have allergic contact dermatitis was nursing. Allergens strongly associated with occupational exposure were thiuram, carbamates, epoxy, and ethylenediamine.
Some contact allergens are more commonly associated with occupational contact dermatitis. Nursing and nursing support are occupations most likely to be overrepresented in contact dermatitis clinics.
职业环境与工人皮肤之间的相互作用可导致刺激性和过敏性接触性皮炎。其他形式的皮炎也可能受到职业暴露的影响。
本研究旨在比较职业性接触性皮炎病例与非职业性接触性皮炎病例的职业和过敏原。
采用北美接触性皮炎组的过敏原进行诊断性斑贴试验,并按照美国国家职业安全与健康研究所的方法进行职业编码。
在2889例因接触性皮炎前来评估的患者中,839例(29%)被诊断为职业性接触性皮炎。在这839例被认定为职业性的病例中,455例(54%)主要为过敏性,270例(32%)主要为刺激性。其余14%为因工作而加重的非接触性皮炎诊断。最常被发现患有过敏性接触性皮炎的职业是护理。与职业暴露密切相关的过敏原是秋兰姆、氨基甲酸盐、环氧树脂和乙二胺。
一些接触性过敏原更常与职业性接触性皮炎相关。护理及护理辅助工作在接触性皮炎诊所中所占比例很可能过高。