Reijenga J, Lee H K
Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, The Netherlands.
J Chromatogr A. 2001 May 4;916(1-2):25-30. doi: 10.1016/s0021-9673(00)01093-1.
The purpose of the contribution is to show how software and the internet have changed the way in which we carry out research, and what additional possibilities these new resources and tools provide. The internet and e-mail broaden our horizon for cooperation. There are no borders for information exchange: our library is a virtual one, electronic databases are at our fingertips. E-mail discussion groups provide an electronic community of CE users. Such forums have provided a basis for worldwide scientific cooperation amongst scientists; the present contribution is only one of several examples. Estimation software provides us with estimates of component properties in those cases where this information is not available from literature or from experiments (an estimated value is better than no value). Several examples will illustrate the use of estimation software in capillary zone electrophoresis and micellar electrokinetic capillary chromatography. Simulation software presents visualization of experimental results to be expected, both as a training tool and as the first step in method development. Other simulations yield valuable insights into phenomena that are not readily accessible experimentally for reasons of size or time-scale.
本文旨在展示软件和互联网如何改变我们开展研究的方式，以及这些新资源和工具带来了哪些额外的可能性。互联网和电子邮件拓宽了我们的合作视野。信息交流没有国界：我们的图书馆是虚拟的，电子数据库触手可及。电子邮件讨论组为毛细管电泳用户提供了一个电子社区。这样的论坛为科学家之间的全球科学合作提供了基础；本文只是众多例子之一。在无法从文献或实验中获取成分属性信息的情况下，估算软件可为我们提供这些属性的估算值（有估算值总比没有好）。几个例子将说明估算软件在毛细管区带电泳和胶束电动毛细管色谱中的应用。模拟软件可呈现预期实验结果的可视化，既作为一种培训工具，也作为方法开发的第一步。其他模拟则能让我们深入了解由于尺寸或时间尺度原因难以通过实验直接观察到的现象。
