Schjönsby H, Hofstad T
Scand J Gastroenterol. 1975;10(3):305-9.
Following preincubation of intrinsic factor- (IF-) bound 57CoB12 with the jejunal sediments of 6 patients with the blind-loop syndrome, the mean uptake by the sediments of IF-57CoB12 (28.1 percent plus or minus 4.2 percent S,E.M.) was significantly higher than the mean uptake by jejunal sediments from 5 control patients (5.8 per cent plus or minus 3.5 percent) (p smaller than 0.01). The uptake by the sediments significantly decreased when the incubations were carried out in the presence of lincomycin and neomycin. The jejunal sediments from the patients with the blind-loop syndrome inhibited the uptake of IF-57CoB12 by perfused rat intestinal segments (p smaller than 0.01), whereas the sediments from the control patients had no such inhibitory effect (p smaller than 0.5).
将结合内因子（IF）的57CoB12与6例盲袢综合征患者的空肠沉淀物进行预温育后，IF-57CoB12被沉淀物的平均摄取量（28.1%±4.2%，标准误）显著高于5例对照患者空肠沉淀物的平均摄取量（5.8%±3.5%）（p<0.01）。当在林可霉素和新霉素存在的情况下进行温育时，沉淀物的摄取量显著降低。盲袢综合征患者的空肠沉淀物抑制了灌注大鼠肠段对IF-57CoB12的摄取（p<0.01），而对照患者的沉淀物没有这种抑制作用（p<0.5）。
