七叶树种子中的三种新三萜皂苷。

Three new triterpene saponins from the seeds of Aesculus chinensis.

作者信息

Zhao J, Yang X W, Hattori M

机构信息

National Laboratory of Natural and Biomimetic Drugs, Beijing University, P R China.

出版信息

Chem Pharm Bull (Tokyo). 2001 May;49(5):626-8. doi: 10.1248/cpb.49.626.

DOI:10.1248/cpb.49.626

PMID:11383619

Abstract

Three new triterpenoid saponins were isolated from the seeds of Aesculus chinensis, and characterized as 22-tigloylprotoaescigenin 3-O-[beta-D-glucopyranosyl (1-->2)] [beta-D-glucopyranosyl (1-->4)]-beta-D-glucopyranosiduronic acid (escin IVg, 1), 22-angeloylprotoaescigenin 3-O-[beta-D-glucopyranosyl (1-->2)] [beta-D-glucopyranosyl (1-->4)]-beta-D-glucopyranosiduronic acid (escin IVh, 2) and 16-angeloyl-21-acetylprotoaescigenin 3-O-[beta-D-glucopyranosyl (1-->2)] [beta-D-glucopyranosyl (1-->4)]-beta-D-glucopyranosiduronic acid (escin VIb, 3), together with two known compounds, escin IIIa (4) and desacylescin 1 (5). Their structures were established on the basis of spectroscopic and chemical evidence.

摘要

从七叶树种子中分离出三种新的三萜皂苷，分别鉴定为22-惕各酰原七叶皂苷元3-O-[β-D-吡喃葡萄糖基(1→2)][β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖醛酸苷（七叶皂苷IVg，1）、22-当归酰原七叶皂苷元3-O-[β-D-吡喃葡萄糖基(1→2)][β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖醛酸苷（七叶皂苷IVh，2）和16-当归酰-21-乙酰原七叶皂苷元3-O-[β-D-吡喃葡萄糖基(1→2)][β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖醛酸苷（七叶皂苷VIb，3），同时还得到两种已知化合物，七叶皂苷IIIa（4）和去酰基七叶皂苷1（5）。它们的结构是根据光谱和化学证据确定的。