七叶树种子中的三种新三萜皂苷。

Three new triterpenoid saponins from the seeds of Aesculus turbinata.

作者信息

Yang Xiu-Wei, Zhao Jing, Hattori Masao

机构信息

The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Science, Peking University, Beijing, China.

出版信息

J Asian Nat Prod Res. 2008 Mar-Apr;10(3-4):259-65. doi: 10.1080/10286020701604904.

DOI:10.1080/10286020701604904

PMID:18335342

Abstract

Three new triterpenoid saponins, named isoescins VIIa (1), VIa (2), and VIIIa (3), were isolated from the seeds of Aesculus turbinata and identified by spectroscopic analysis and chemical hydrolysis. Their structures were established as 21beta-O-tigloyl-28-O-acetylprotoaescigenin 3beta-O-[beta-d-galactopyranosyl(1 --> 2)][beta-d-glucopyranosyl(1 --> 4)]-beta-d-glucopyranosiduronic acid (Isoescin VIIa, 1), 21beta-O-(2-methylbutyryl)-28-O-acetylprotoaescigenin 3beta-O-[beta-d-glucopyranosyl(1 --> 2)] [beta-d-glucopyranosyl(1 --> 4)]-beta-d-glucopyranosiduronic acid (Isoescin VIa, 2), and 21beta-O-angeloyl-28-O-acetylbarringtogenol C 3beta-O-[beta-d-glucopyranosyl(1 --> 2)] [beta-d-glucopyranosyl(1 --> 4)]-beta-d-glucopyranosiduronic acid (Isoescin VIIIa, 3).

摘要

从日本七叶树种子中分离出三种新的三萜皂苷，命名为异七叶皂苷VIIa（1）、VIa（2）和VIIIa（3），并通过光谱分析和化学水解进行鉴定。它们的结构确定为21β -O-惕各酰基-28-O-乙酰基原七叶皂苷元3β -O-[β -D-吡喃半乳糖基（1→2）][β -D-吡喃葡萄糖基（1→4）]-β -D-吡喃葡萄糖醛酸苷（异七叶皂苷VIIa，1）、21β -O-（2-甲基丁酰基）-28-O-乙酰基原七叶皂苷元3β -O-[β -D-吡喃葡萄糖基（1→2）][β -D-吡喃葡萄糖基（1→4）]-β -D-吡喃葡萄糖醛酸苷（异七叶皂苷VIa，2）和21β -O-当归酰基-28-O-乙酰基巴灵通醇C 3β -O-[β -D-吡喃葡萄糖基（1→2）][β -D-吡喃葡萄糖基（1→4）]-β -D-吡喃葡萄糖醛酸苷（异七叶皂苷VIIIa，3）。