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再次主动脉根部置换术:31例患者的经验

Redo aortic root replacement: experience with 31 patients.

作者信息

Raanani E, David T E, Dellgren G, Armstrong S, Ivanov J, Feindel C M

机构信息

Division of Cardiovascular Surgery, Toronto General Hospital, and University of Toronto, Ontario, Canada.

出版信息

Ann Thorac Surg. 2001 May;71(5):1460-3. doi: 10.1016/s0003-4975(01)02410-9.

Abstract

BACKGROUND

Aortic root re-replacement is being performed with increased frequency. Limited information is available regarding the surgical approaches and clinical outcomes of this reoperation.

METHODS

Between May 1980 and May 1999, 31 patients (mean age, 45 +/- 15 years) underwent redo composite replacement of the aortic valve and ascending aorta. Indications for reoperation were prosthetic valve endocarditis in 12 patients (39%), failed biological valve in 17 (55%), and false aneurysm in 2 (6%). At reoperation, mechanical valves were implanted in 24 patients and biologic valves in 7. All patients with endocarditis had annular abscess and required reconstruction of the left ventricular outflow tract before implantation of a new valved conduit. Mechanical valves were used in 24 patients, aortic homograft in 4, and bioprosthetic valves in 3. The coronary button technique was used to reimplant the coronary arteries whenever possible. Extension of one or both coronary arteries with a short segment of saphenous vein or a synthetic graft was used in 16 patients (52%). The aortic arch was replaced in 7 patients (23%).

RESULTS

There was one operative death (3%) because of rupture of an abdominal aortic aneurysm. The mean follow-up was 47 +/- 46 months and was 100% complete. There were five late deaths (16%), three of which were cardiac related. The actuarial survival was 71% +/- 12% at 5 years. Three patients experienced recurrent prosthetic valve endocarditis 4 months to 8 years after operation. The 8-year freedom from endocarditis for patients operated on for endocarditis was 82% +/- 11% compared with 100% for those operated on for other reasons (p = 0.1). At the last follow-up, 21 of 25 survivors (84%) were in New York Heart Association functional classes I or II, and 4 were in class III.

CONCLUSIONS

Redo aortic root replacement can be performed with good early and late results. Patients operated on for prosthetic root endocarditis may have an increased risk of recurrent late endocarditis.

摘要

背景

主动脉根部再次置换手术的实施频率日益增加。关于这种再次手术的手术方式和临床结果的信息有限。

方法

1980年5月至1999年5月期间,31例患者(平均年龄45±15岁)接受了主动脉瓣和升主动脉再次复合置换术。再次手术的指征为人工瓣膜心内膜炎12例(39%)、生物瓣膜失效17例(55%)、假性动脉瘤2例(6%)。再次手术时,24例患者植入机械瓣膜,7例植入生物瓣膜。所有心内膜炎患者均有瓣环脓肿,在植入新的带瓣管道前需要重建左心室流出道。24例患者使用机械瓣膜,4例使用主动脉同种异体移植物,3例使用生物人工瓣膜。只要有可能,均采用冠状动脉纽扣技术重新植入冠状动脉。16例患者(52%)使用一段短的大隐静脉或人工血管延长一根或两根冠状动脉。7例患者(23%)进行了主动脉弓置换。

结果

1例患者(3%)因腹主动脉瘤破裂死亡。平均随访时间为47±46个月,随访完整率为100%。有5例晚期死亡(16%),其中3例与心脏相关。5年时的精算生存率为71%±12%。3例患者在术后4个月至8年发生人工瓣膜心内膜炎复发。因心内膜炎接受手术的患者8年无感染性心内膜炎生存率为82%±11%,而因其他原因接受手术的患者为100%(p=0.1)。在最后一次随访时,25例幸存者中有21例(84%)纽约心脏协会心功能分级为I或II级,4例为III级。

结论

主动脉根部再次置换术可取得良好的早期和晚期效果。因人工瓣膜根部心内膜炎接受手术的患者晚期感染性心内膜炎复发风险可能增加。

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