Karangelis Dimos, Tzertzemelis Dimitrios, Demis Alexandros A, Economidou Stella, Panagiotou Matthew
Cardiac Surgery Department, Athens Medical Center, Distomou 5, Amaroussio 151 25, Greece.
J Thorac Dis. 2018 Dec;10(12):6733-6741. doi: 10.21037/jtd.2018.11.61.
We retrospectively reviewed our experience with the modified Bentall procedure and evaluated the short- and long-term results over a period of 18 years.
Between 1999 and 2017, 89 patients with a mean age of 57.3±13.9 years underwent the modified Bentall operation with a slight modification for the correction of aortic root disease.
The operative mortality was 1.1% while the overall early mortality rate, defined as death within 30 days of initial hospitalization, was 2.2% (2/89). Logistic regression analysis revealed that increased Euroscore and aortic cross-clamp times were associated with greater likelihood for complications. The overall survival rates for the 89 patients (including deaths occurred at the initial hospitalization) were 93.0% (SE =3.0%) at 6 months, 93.0% (SE =3.0%) at 1 year, 89% (SE =5.0%) at 5 years and 73.0% (SE =5.0%) at 10, 15 and 18 years. Multiple Cox regression analysis for survival identified that increased aortic cross-clamp time, increased age, having a concomitant cardiac procedure and increased NYHA Class were associated with greater hazard. Left ventricular remodeling was assessed by means of echocardiography preoperatively and 1, 3, 6 and 12 months postoperatively.
According to our experience, the Bentall procedure is a safe procedure, provides optimal long-term survival and can still be regarded as the gold standard procedure for aortic root replacement.
我们回顾性分析了改良Bentall手术的经验,并评估了18年间的短期和长期结果。
1999年至2017年间,89例平均年龄为57.3±13.9岁的患者接受了改良Bentall手术,该手术在纠正主动脉根部疾病方面略有改良。
手术死亡率为1.1%,而总体早期死亡率(定义为初次住院30天内死亡)为2.2%(2/89)。逻辑回归分析显示,欧洲心脏手术风险评估系统(Euroscore)增加和主动脉阻断时间延长与并发症发生的可能性增加相关。89例患者(包括初次住院时死亡的患者)的总体生存率在6个月时为93.0%(标准误=3.0%),1年时为93.0%(标准误=3.0%),5年时为89%(标准误=5.0%),10年、15年和18年时为73.0%(标准误=5.0%)。生存的多因素Cox回归分析确定,主动脉阻断时间延长、年龄增加、同期进行心脏手术和纽约心脏协会(NYHA)心功能分级增加与更高的风险相关。术前以及术后1、3、6和12个月通过超声心动图评估左心室重构。
根据我们的经验,Bentall手术是一种安全的手术,可提供最佳的长期生存率,仍可被视为主动脉根部置换的金标准手术。