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采用改良Bentall纽扣技术进行全根部置换的18年临床经验。

Eighteen years of clinical experience with a modification of the Bentall button technique for total root replacement.

作者信息

Karangelis Dimos, Tzertzemelis Dimitrios, Demis Alexandros A, Economidou Stella, Panagiotou Matthew

机构信息

Cardiac Surgery Department, Athens Medical Center, Distomou 5, Amaroussio 151 25, Greece.

出版信息

J Thorac Dis. 2018 Dec;10(12):6733-6741. doi: 10.21037/jtd.2018.11.61.

Abstract

BACKGROUND

We retrospectively reviewed our experience with the modified Bentall procedure and evaluated the short- and long-term results over a period of 18 years.

METHODS

Between 1999 and 2017, 89 patients with a mean age of 57.3±13.9 years underwent the modified Bentall operation with a slight modification for the correction of aortic root disease.

RESULTS

The operative mortality was 1.1% while the overall early mortality rate, defined as death within 30 days of initial hospitalization, was 2.2% (2/89). Logistic regression analysis revealed that increased Euroscore and aortic cross-clamp times were associated with greater likelihood for complications. The overall survival rates for the 89 patients (including deaths occurred at the initial hospitalization) were 93.0% (SE =3.0%) at 6 months, 93.0% (SE =3.0%) at 1 year, 89% (SE =5.0%) at 5 years and 73.0% (SE =5.0%) at 10, 15 and 18 years. Multiple Cox regression analysis for survival identified that increased aortic cross-clamp time, increased age, having a concomitant cardiac procedure and increased NYHA Class were associated with greater hazard. Left ventricular remodeling was assessed by means of echocardiography preoperatively and 1, 3, 6 and 12 months postoperatively.

CONCLUSIONS

According to our experience, the Bentall procedure is a safe procedure, provides optimal long-term survival and can still be regarded as the gold standard procedure for aortic root replacement.

摘要

背景

我们回顾性分析了改良Bentall手术的经验,并评估了18年间的短期和长期结果。

方法

1999年至2017年间,89例平均年龄为57.3±13.9岁的患者接受了改良Bentall手术,该手术在纠正主动脉根部疾病方面略有改良。

结果

手术死亡率为1.1%,而总体早期死亡率(定义为初次住院30天内死亡)为2.2%(2/89)。逻辑回归分析显示,欧洲心脏手术风险评估系统(Euroscore)增加和主动脉阻断时间延长与并发症发生的可能性增加相关。89例患者(包括初次住院时死亡的患者)的总体生存率在6个月时为93.0%(标准误=3.0%),1年时为93.0%(标准误=3.0%),5年时为89%(标准误=5.0%),10年、15年和18年时为73.0%(标准误=5.0%)。生存的多因素Cox回归分析确定,主动脉阻断时间延长、年龄增加、同期进行心脏手术和纽约心脏协会(NYHA)心功能分级增加与更高的风险相关。术前以及术后1、3、6和12个月通过超声心动图评估左心室重构。

结论

根据我们的经验,Bentall手术是一种安全的手术,可提供最佳的长期生存率,仍可被视为主动脉根部置换的金标准手术。

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