Ura M, Sakata R, Nakayama Y, Arai Y, Oshima S, Noda K, Kitaoka M
Department of Cardiovascular Surgery, Kumamoto Central Hospital, Japan.
Ann Thorac Surg. 2001 May;71(5):1485-90. doi: 10.1016/s0003-4975(01)02496-1.
Little is known about the anatomic limitations of in situ right internal thoracic artery (RITA) grafting to the circumflex artery.
To evaluate the technical aspects and outcome of revascularization of the proximal and distal major branches of the circumflex artery (obtuse marginal [OM] branch and posterolateral [PL] branch), a total of 145 patients who possessed a graftable branch of the circumflex artery were enrolled into the prospective project. There were 73 patients who had the PL branch as a primary target and 72 patients with OM branches, which were allocated by a blinded observer who reviewed the preoperative angiography.
Changes of primary target vessels were required in 9 patients (6.2%), yielding an overall success rate of RITA grafting of 93.8%. The success rates of RITA grafting to the OM branch and the PL branch were 95.8% (69/72; CI 88.3% to 99.1%) and 91.7% (67/73; CI 83.0% to 96.9%), respectively. The univariate analysis identified grafting under hypothermic ventricular fibrillation as predictors of inability to use in situ RITA grafting for revascularization of the circumflex artery. RITA grafting to the PL branch is not identified as a predictor. Postoperative angiography in 136 patients revealed only one occlusion (0.75%) of the RITA graft anastomosed to the marginal artery. There were no significant differences in patency rates between left and right ITA grafts.
This prospective study showed that in situ RITA was, in most cases, able to reach most branches of the major circumflex artery and demonstrated an excellent patency rate.
关于原位右胸廓内动脉(RITA)移植至回旋支动脉的解剖学限制知之甚少。
为评估回旋支动脉近端和远端主要分支(钝缘支[OM]和后外侧支[PL])血运重建的技术要点和结果,共有145例具有可移植回旋支动脉分支的患者纳入该前瞻性项目。73例患者以PL支为主要目标,72例患者以OM支为目标,由一名盲法观察者根据术前血管造影进行分配。
9例患者(6.2%)需要更换主要目标血管,RITA移植的总体成功率为93.8%。RITA移植至OM支和PL支的成功率分别为95.8%(69/72;CI 88.3%至99.1%)和91.7%(67/73;CI 83.0%至96.9%)。单因素分析确定在低温心室颤动下进行移植是无法使用原位RITA移植进行回旋支动脉血运重建的预测因素。未发现RITA移植至PL支是预测因素。136例患者术后血管造影显示,与边缘动脉吻合的RITA移植血管仅1例闭塞(0.75%)。左右胸廓内动脉移植血管的通畅率无显著差异。
这项前瞻性研究表明,在大多数情况下,原位RITA能够到达回旋支动脉的大多数分支,并显示出优异的通畅率。