Bonacchi M, Battaglia F, Prifti E, Leacche M, Nathan N S, Sani G, Popoff G
Department of Cardiac Surgery, University of Florence, Florence, Italy.
Heart. 2005 Feb;91(2):195-202. doi: 10.1136/hrt.2003.024091.
To investigate in a retrospective study the technical aspects of using the in situ bilateral internal mammary arteries (IMAs), with the right IMA (RIMA) used for revascularisation of the circumflex system, and to evaluate early and late outcome.
Between January 1997 and July 2003, 552 consecutive patients underwent grafting of the circumflex artery system with an in situ skeletonised RIMA routed through the transverse sinus (eventually retrocaval). Mean (SD) age was 63.8 (11) years. 331 (60%) patients underwent total arterial myocardial revascularisation. Mean follow up was 26 (9) months.
The success rate of skeletonised RIMA grafting to the circumflex branch was 100%. There were 19 (3.4%) in-hospital deaths. Perioperative myocardial infarction occurred in 12 (2.2%) patients. In 155 patients undergoing postoperative angiography, two had an occluded RIMA and a string-like phenomenon was seen in three RIMA and one left IMA (LIMA). Three RIMA and three LIMA had stenotic lesions. The patency rates of RIMA and LIMA were 94% and 97.4%, respectively. Strong predictors of non-functional IMA grafts were a recipient coronary artery diameter of < 1.5 mm (p = 0.022), < 60% stenosis of the recipient coronary artery (p = 0.015), diffuse stenotic lesions of the recipient coronary artery (p = 0.018), and a small IMA calibre (p = 0.0001). Cumulative actuarial survival at three years was 96.4% and event-free cumulative survival was 93.8%.
Use of the bilateral IMAs offers the possibility of constructing various configurations, making total arterial myocardial revascularisation possible with a minimum number of arterial conduits. Use of the skeletonised RIMA through the transverse sinus and eventually retrocavally can reach most branches of the circumflex system and is associated with an excellent patency rate. Patients who received bilateral IMA grafts for left coronary system revascularisation had improved early and late outcomes and decreased risk of death, reoperation, and angioplasty.
在一项回顾性研究中,探讨使用原位双侧乳内动脉(IMA)的技术细节,其中右乳内动脉(RIMA)用于回旋支系统的血运重建,并评估早期和晚期结果。
1997年1月至2003年7月期间,552例连续患者接受了原位骨骼化RIMA经横窦(最终经腔静脉后)移植至回旋支动脉系统的手术。平均(标准差)年龄为63.8(11)岁。331例(60%)患者接受了全动脉心肌血运重建。平均随访时间为26(9)个月。
骨骼化RIMA移植至回旋支分支的成功率为100%。住院死亡19例(3.4%)。围手术期心肌梗死发生在12例(2.2%)患者中。在155例接受术后血管造影的患者中,2例RIMA闭塞,3例RIMA和1例左乳内动脉(LIMA)出现条索状现象。3例RIMA和3例LIMA有狭窄病变。RIMA和LIMA的通畅率分别为94%和97.4%。IMA移植无功能的强预测因素为受体冠状动脉直径<1.5 mm(p = 0.022)、受体冠状动脉狭窄<60%(p = 0.015)、受体冠状动脉弥漫性狭窄病变(p = 0.018)和IMA管径小(p = 0.0001)。三年累计精算生存率为96.4%,无事件累计生存率为93.8%。
使用双侧IMA提供了构建各种构型的可能性,使全动脉心肌血运重建能够以最少数量的动脉管道实现。通过横窦并最终经腔静脉后使用骨骼化RIMA可到达回旋支系统的大多数分支,且通畅率极佳。接受双侧IMA移植进行左冠状动脉系统血运重建的患者早期和晚期结果得到改善,死亡、再次手术和血管成形术风险降低。