Larsen M J
Royal Dental College, Aarhus, Denmark.
Caries Res. 2001 May-Jun;35(3):229-34. doi: 10.1159/000047461.
Fluoride has been suggested to prevent erosion of the teeth, either after a topical treatment of the teeth or by addition of fluoride to the acidic drink. The main aim of the present study was to describe the dissolution of calcium fluoride in some soft drinks and orange juice and compare it with the amounts of calcium fluoride left on the enamel surfaces after a topical treatment. A further aim was to describe the dissolution of enamel in soft drinks and juice saturated for 3 days with solid calcium fluoride. Solid calcium fluoride was suspended in each of 10 soft drinks and orange juices and gently agitated for 72 h, after which the drinks were analyzed for calcium, phosphate and fluoride and pH was determined. To examine the erosion-preventive effect of the calcium fluoride-rich drink, intact teeth were exposed to the drinks with or without calcium fluoride. It was found that from 6 to 45 mg of calcium fluoride was dissolved per liter of drink. The more acidic the drink, the more calcium fluoride was dissolved, presumably due to HF formation. The teeth exposed to the soft drinks all showed erosion-like lesions. Very little effect of the 4-6 ppm ionic fluoride dissolved in the soft drinks was observed. In orange juice, however, the dissolved calcium fluoride established a saturation with respect to fluorapatite and consequently, the erosion-like lesion was replaced by a caries-like lesion. In conclusion, the acidic soft drinks are capable of dissolving considerable amounts of calcium fluoride and the erosion-preventive effect of even high fluoride concentrations is limited.
有人提出，无论是在对牙齿进行局部治疗后，还是在酸性饮料中添加氟化物，氟化物都能预防牙齿侵蚀。本研究的主要目的是描述氟化钙在一些软饮料和橙汁中的溶解情况，并将其与局部治疗后留在牙釉质表面的氟化钙量进行比较。另一个目的是描述在固体氟化钙饱和3天的软饮料和果汁中牙釉质的溶解情况。将固体氟化钙悬浮在10种软饮料和橙汁中，轻轻搅拌72小时，然后分析饮料中的钙、磷和氟，并测定pH值。为了研究富含氟化钙的饮料的防侵蚀效果，将完整的牙齿暴露于含或不含氟化钙的饮料中。结果发现，每升饮料中溶解了6至45毫克的氟化钙。饮料酸性越强，溶解的氟化钙越多，可能是由于形成了氢氟酸。暴露于软饮料中的牙齿均出现了类似侵蚀的病变。几乎未观察到软饮料中溶解的4 - 6 ppm离子氟化物有什么效果。然而，在橙汁中，溶解的氟化钙形成了相对于氟磷灰石的饱和度，因此，类似侵蚀的病变被类似龋齿的病变所取代。总之，酸性软饮料能够溶解大量的氟化钙，即使是高氟浓度的防侵蚀效果也很有限。
