Larsen M J, Richards A
Royal Dental College, University of Aarhus, Denmark.
Caries Res. 2002 Jan-Feb;36(1):75-80. doi: 10.1159/000057595.
The main aim of the present study was to compare the erosive capabilities of some fruit-flavoured drinks, fresh or saturated with CaF2, with their content of acids and with previous results from some carbonated soft drinks. The other aim was to measure and compare the rates of dissolution of CaF2 in some carbonated and non-carbonated drinks and water. Seven commercially available fruit-flavoured drinks were diluted for drinking. Two human molars, each with two approximately 4 x 4 mm windows, were exposed continuously to 500 ml of each drink with or without prior equilibration with CaF2 under gentle agitation for 48 h. The depths of the erosions were then measured on microradiographs made from sections. Dissolution rate of CaF2 was measured by suspending 0.5 g of the salt in 0.5 litre of the drinks for 2, 10 and 60 min followed by solution analysis. The pH of the drinks was 2.83-3.51. The amount of NaOH required to bring pH to 5.5 ranged from 12-42 mmol/l, which is more than the amount necessary for most carbonated soft drinks. Equilibration with CaF2 gave total fluoride concentrations of 3-8 ppm. The depths of the lesions induced by the drinks without added fluoride were 450-625 microm whilst those developed by the drinks equilibrated with CaF2 were 350-625 microm. The dissolution of CaF2 was faster in the carbonated drinks and in distilled water than in the non-carbonated drinks. In conclusion, non-carbonated fruit-flavoured drinks contain considerable amounts of acids which, in vitro, induce erosions in teeth similar to those induced by carbonated soft drinks. Saturation with CaF2 reduced the in vitro development of erosions by 28% induced by drinks with pH above 3; in drinks with pH below 3, erosions were not affected by pH, despite total fluoride concentrations of up to 20 ppm.
本研究的主要目的是比较一些水果味饮料(新鲜的或用CaF₂饱和的)的侵蚀能力与其酸含量,并与一些碳酸软饮料的先前结果进行比较。另一个目的是测量和比较CaF₂在一些碳酸饮料、非碳酸饮料和水中的溶解速率。将七种市售水果味饮料稀释后供饮用。两颗人类磨牙,每颗有两个约4×4毫米的窗口,在温和搅拌下连续暴露于500毫升每种饮料中,饮料添加或未添加CaF₂进行预平衡,持续48小时。然后在由切片制成的显微放射照片上测量侵蚀深度。通过将0.5克盐悬浮在0.5升饮料中2、10和60分钟,然后进行溶液分析来测量CaF₂的溶解速率。饮料的pH值为2.83 - 3.51。将pH值调至5.5所需的NaOH量为12 - 42毫摩尔/升,这比大多数碳酸软饮料所需的量更多。用CaF₂平衡后,总氟浓度为3 - 8 ppm。未添加氟的饮料引起的病变深度为450 - 625微米,而用CaF₂平衡的饮料引起的病变深度为350 - 625微米。CaF₂在碳酸饮料和蒸馏水中的溶解速度比在非碳酸饮料中快。总之,非碳酸水果味饮料含有大量酸,在体外会引起牙齿侵蚀,类似于碳酸软饮料引起的侵蚀。用CaF₂饱和可使pH值高于3的饮料引起的体外侵蚀发展减少28%;在pH值低于3的饮料中,尽管总氟浓度高达20 ppm,侵蚀不受pH值影响。