自身免疫性肝病。当前标准与未来方向。

Autoimmune liver disease. Current standards, future directions.

作者信息

Gish R G, Mason A

机构信息

Departments of Medicine and Transplantation, California Pacific Medical Center, San Francisco, California, USA.

出版信息

Clin Liver Dis. 2001 May;5(2):287-314. doi: 10.1016/s1089-3261(05)70167-7.

DOI:10.1016/s1089-3261(05)70167-7

PMID:11385965

Abstract

The diagnosis and management of autoimmune hepatitis continues to evolve as new diagnostic tests and new therapies are added to the armamentarium. Also encouraging are the advances in the understanding of the human immune system and its involvement in the origin and course of auto immune diseases in general and in the variants of autoimmune liver disease. Promising changes are expected in the next few years as new medications become available to the practicing hepatologist. New immune tests may allow therapies to be customized to patients, and antiviral therapies may also eventually be used in the management of this autoimmune liver diseases.

摘要

随着新的诊断测试和新疗法被纳入可用手段，自身免疫性肝炎的诊断和管理持续发展。对人类免疫系统及其在自身免疫性疾病总体起源和病程以及自身免疫性肝病变体中的作用的认识取得进展，这同样令人鼓舞。随着新药物可供执业肝病学家使用，预计未来几年会有令人期待的变化。新的免疫测试可能使治疗能够根据患者情况定制，抗病毒疗法最终也可能用于这种自身免疫性肝病的管理。