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临床未识别的椎动脉夹层作为小脑梗死的病因

Clinically unidentified dissection of vertebral artery as a cause of cerebellar infarction.

作者信息

Iwase H, Kobayashi M, Kurata A, Inoue S

机构信息

Departments of Forensic Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

出版信息

Stroke. 2001 Jun;32(6):1422-4. doi: 10.1161/01.str.32.6.1422.

Abstract

BACKGROUND AND PURPOSE

Dissection of vertebral arteries has been reported in association with minor neck movements without signs of trauma on the surface of the neck. In addition, injury of a vertebral artery can cause brain infarctions. However, few cases have been reported in which fatal brain infarction was due to nonocclusive, clinically undetected, traumatic thrombus formation in a vertebral artery.

CASE DESCRIPTION

A 62-year-old man was hit by a car, and a right cerebellar infarction was found the day after the accident. The cause of the infarction could not be detected by angiography. Although the patient recovered favorably after surgical removal of the right lateral hemisphere of the cerebellum, he died suddenly 2 weeks after the accident. An autopsy and a microscopic study revealed pulmonary thromboembolism and organizing traumatic lesions of the right vertebral artery without occlusion or noteworthy stenosis of the artery.

CONCLUSIONS

We concluded that the patient sustained traumatic lesions of the right vertebral artery during the traffic accident 2 weeks before death and that his cerebellar infarction was due to a thrombus resulting from these traumatic lesions.

摘要

背景与目的

有报道称,椎动脉夹层与轻微颈部活动相关,且颈部表面无创伤迹象。此外,椎动脉损伤可导致脑梗死。然而,因椎动脉非闭塞性、临床未检测到的创伤性血栓形成导致致命性脑梗死的病例报道较少。

病例描述

一名62岁男性被汽车撞倒,事故次日发现右侧小脑梗死。血管造影未检测到梗死原因。尽管患者在手术切除右侧小脑半球后恢复良好,但在事故2周后突然死亡。尸检和显微镜检查显示肺血栓栓塞以及右侧椎动脉的组织化创伤性病变,动脉无闭塞或明显狭窄。

结论

我们得出结论,患者在死亡前2周的交通事故中右侧椎动脉受到创伤性损伤,其小脑梗死是由这些创伤性损伤导致的血栓引起的。

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