Paul K, Patel S S
Department of Pediatrics, Rainbow Babies and Children's Hospital, Cleveland, OH 44106, USA.
Clin Infect Dis. 2001 Jul 1;33(1):54-61. doi: 10.1086/320883. Epub 2001 May 23.
Eikenella corrodens is a slow-growing, gram-negative, nonmotile, facultative rod that can cause infection in humans. Although the clinical characteristics of Eikenella infections in adults are well described, the literature regarding Eikenella infections in children is lacking. Thirteen cases of Eikenella infection in children and adolescents reported from a hospital and an additional 41 cases from the literature were reviewed. Eikenella species can be serious pediatric pathogens, particularly when there is an exposure to human oral secretions. Empirical therapy used to manage most oropharyngeal flora may be ineffective against Eikenella species. The treatment of choice for children and adolescents who are infected with Eikenella species includes a combination of surgical management and antibiotics.
啮蚀艾肯菌是一种生长缓慢、革兰氏阴性、无运动性的兼性杆菌，可导致人类感染。虽然成人艾肯菌感染的临床特征已有充分描述，但关于儿童艾肯菌感染的文献却很匮乏。对一家医院报告的13例儿童和青少年艾肯菌感染病例以及文献中的另外41例病例进行了回顾。艾肯菌属可能是严重的儿科病原体，尤其是在接触人类口腔分泌物的情况下。用于治疗大多数口咽菌群的经验性疗法可能对艾肯菌属无效。感染艾肯菌属的儿童和青少年的首选治疗方法包括手术治疗和抗生素联合使用。
